O
Onosereme Ofoman
Publications - 6
Citations - 1056
Onosereme Ofoman is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 6, co-authored 6 publications receiving 1056 citations.
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Journal ArticleDOI
mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant
Wilfredo F. Garcia-Beltran,K. S. St. Denis,Angelique Hoelzemer,Evan C. Lam,Adam Nitido,M. Sheehan,Cristhian Berríos,Onosereme Ofoman,Christina C. Chang,Blake M. Hauser,Jared Feldman,Alex Roederer,David Gregory,Mark C. Poznansky,Aaron G. Schmidt,A. John Iafrate,Vivek Naranbhai,Alejandro B. Balazs +17 more
TL;DR: In this article , the authors measured the neutralization potency of sera from 88 mRNA-1273, 111 BNT162b, and 40 Ad26.1.1/B.COV2.
Journal ArticleDOI
T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals
Vivek Naranbhai,Anusha Nathan,C. Kaseke,Cristhian Berríos,Ashok Khatri,Shawn Choi,Matthew A. Getz,Rhoda Tano-Menka,Onosereme Ofoman,Alton C. Gayton,Fernando Senjobe,Zezhou Zhao,K. S. St. Denis,Evan C. Lam,Mary Carrington,Wilfredo F. Garcia-Beltran,Alejandro B. Balazs,Bruce D. Walker,A. John Iafrate,Gaurav D. Gaiha +19 more
TL;DR: In this article , the authors show that T cell responses in individuals with prior infection, vaccination, both prior infection and vaccination, and boosted vaccination are largely preserved to Omicron spike and non-spike proteins.
Journal ArticleDOI
T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals
Vivek Naranbhai,Anusha Nathan,C. Kaseke,Cristhian Berríos,Ashok Khatri,Shawn Choi,Matthew A. Getz,Rhoda Tano-Menka,Onosereme Ofoman,Alton C. Gayton,Fernando Senjobe,Zezhou Zhao,K. S. St. Denis,Evan C. Lam,Mary Carrington,Wilfredo F. Garcia-Beltran,Alejandro B. Balazs,Bruce D. Walker,A. John Iafrate,Gaurav D. Gaiha +19 more
TL;DR: Garcia-Beltran et al. as mentioned in this paper reported that T cells from most SARS-CoV-2 infected and/or vaccinated individuals have preserved reactivity to the Omicron variant, and their reactivity is enhanced by booster vaccination.
Posted ContentDOI
T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all prior infected and vaccinated individuals
Vivek Naranbhai,Anusha Nathan,C. Kaseke,Cristhian Berríos,Ashok Khatri,Shawn Choi,Matthew A. Getz,Rhoda Tano-Menka,Onosereme Ofoman,Alton C. Gayton,Fernando Senjobe,Kerri St. Denis,Evan C. Lam,Wilfredo F. Garcia-Beltran,Alejandro B. Balazs,Bruce D. Walker,A. John Iafrate,Gaurav D. Gaiha +17 more
TL;DR: It is shown that T cell responses in individuals with prior infection, vaccination, both prior infection and vaccination, and boosted vaccination are largely preserved to Omicron spike and non-spike proteins, however, a subset of individuals with a >50% reduction in T cell reactivity to the Omicrons spike are identified.
Posted ContentDOI
Preferential expansion of cross-reactive pre-existing switched memory B cells that recognize the SARS-CoV-2 Omicron variant Spike protein
Cory A. Perugino,Hang Liu,Jared Feldman,Blake M. Hauser,Catherine Jacob-Dolan,Anusha Nathan,C. Kaseke,Rhoda Tano-Menka,Matthew A. Getz,Fernando Senjobe,Cristhian Berríos,Onosereme Ofoman,Jacob E. Lemieux,Marcia B. Goldberg,Kerstin Nundel,Ann M. Moormann,Ann Marshak-Rothstein,John Iafrate,Gaurav D. Gaiha,Richelle C. Charles,Alejandro B. Balazs,Vivek Naranbhai,Aaron G. Schmidt,Shiv Pillai +23 more
TL;DR: In previously unvaccinated and uninfected individuals, non-RBD SARS-CoV-2 spike specific B cells were prominent in two distinct, durable, resting, cross-reactive, preexisting switched memory B cell compartments.