O
Orla Moriarty
Researcher at National University of Ireland, Galway
Publications - 18
Citations - 1576
Orla Moriarty is an academic researcher from National University of Ireland, Galway. The author has contributed to research in topics: Allodynia & Hyperalgesia. The author has an hindex of 14, co-authored 18 publications receiving 1272 citations. Previous affiliations of Orla Moriarty include UCL Institute of Child Health & Dublin City University.
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Journal ArticleDOI
The effect of pain on cognitive function: a review of clinical and preclinical research.
TL;DR: The anatomical, neurochemical and molecular substrates common to both cognitive processing and supraspinal pain processing are described, and the evidence for their involvement in pain-related cognitive impairment is presented.
Journal ArticleDOI
Minocycline modulates neuropathic pain behaviour and cortical M1–M2 microglial gene expression in a rat model of depression
TL;DR: It is revealed that SNL-induced mechanical allodynia in OB rats was attenuated by chronic minocycline at almost all time-points over a 2week testing period, an effect observed only from day 10 post-SNL in sham rats.
Journal ArticleDOI
Microglial P2X4R-evoked pain hypersensitivity is sexually dimorphic in rats.
Josiane C.S. Mapplebeck,Rebecca Dalgarno,YuShan Tu,Orla Moriarty,Simon Beggs,Charlie H.T. Kwok,Katherine Halievski,Sofia Assi,Jeffrey S. Mogil,Tuan Trang,Michael W. Salter +10 more
TL;DR: The findings demonstrate the existence of sexually dimorphic pain signalling in rats, suggesting that this sex difference is evolutionarily conserved, at least across rodent species.
Journal ArticleDOI
Cognition and pain.
Orla Moriarty,David P. Finn +1 more
TL;DR: Progress has been made in understanding the complex relationship between pain and cognitive function, however, both synthesis of current research findings and further novel research studies are required to maximize the therapeutic potential.
Journal ArticleDOI
Cognitive Impairment in Patients with Chronic Neuropathic or Radicular Pain: An Interaction of Pain and Age.
Orla Moriarty,Nancy Ruane,Nancy Ruane,David O'Gorman,David O'Gorman,Chris H. Maharaj,Chris H. Maharaj,Caroline Mitchell,Caroline Mitchell,Kiran Sarma,David P. Finn,Brian E. McGuire,Brian E. McGuire +12 more
TL;DR: This study supports and extends previous research indicating that chronic pain is associated with impaired memory and attention and specifically investigated the interaction effect of pain and age on cognitive performance.