O
Otylia Kowal-Bielecka
Researcher at Medical University of Białystok
Publications - 117
Citations - 10847
Otylia Kowal-Bielecka is an academic researcher from Medical University of Białystok. The author has contributed to research in topics: Interstitial lung disease & Scleroderma. The author has an hindex of 32, co-authored 111 publications receiving 8846 citations. Previous affiliations of Otylia Kowal-Bielecka include University of Zurich.
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Journal ArticleDOI
Angiopoietins-1 and -2 are differentially expressed in the sera of patients with systemic sclerosis: high angiopoietin-2 levels are associated with greater severity and higher activity of the disease
Maøgorzata Michalska-Jakubus,Otylia Kowal-Bielecka,Grażyna Chodorowska,Marek Bielecki,Dorota Krasowska +4 more
TL;DR: Ang-2 was significantly increased in SSc patients with more advanced capillary damage, as indicated by the presence of late capillaroscopic pattern, than in those with less severe microangiopathy (active pattern), and in S Sc patients with intermediate/late stage of disease than in S sc subjects with early disease.
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Outcomes of limited cutaneous systemic sclerosis patients: Results on more than 12,000 patients from the EUSTAR database.
Camelia Frantz,Dörte Huscher,Jérôme Avouac,Eric Hachulla,Alexandra Balbir-Gurman,Gabriela Riemekasten,Elise Siegert,M. G. Lazzaroni,Patricia Carreira,Serena Vettori,Elisabetta Zanatta,Susanne Ullman,László Czirják,Otylia Kowal-Bielecka,Oliver Distler,Marco Matucci-Cerinic,Yannick Allanore +16 more
TL;DR: Skin disease was remarkably stable in the majority of LcSSc patients with >80% having a change lower than ±4 units of mRSS at 12, 24 and 36 months follow-up, and FVC changes over time were very similar between LCSSc and DcS sc.
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European League Against Rheumatism (EULAR) Scleroderma Trial and Research group (EUSTAR) recommendations for the treatment of systemic sclerosis: methods of elaboration and results of systematic literature research.
Jérôme Avouac,Otylia Kowal-Bielecka,Robert Landewé,S. Chwiesko,I. Miniati,L. Czirják,P. J. Clements,Christopher P. Denton,Dominique Farge,Kim Fligelstone,I. Földvari,Daniel E. Furst,Ulf Müller-Ladner,James R. Seibold,Richard M. Silver,K. Takehara,B. Garay Toth,A Tyndall,Gabriele Valentini,F.H.J. van den Hoogen,F. M. Wigley,Francesco Zulian,Marco Matucci-Cerinic +22 more
TL;DR: Methods and procedures used to build recommendations for the drug treatment of systemic sclerosis, combining an evidence based approach and expert opinion are described.
Journal ArticleDOI
Measures of response in clinical trials of systemic sclerosis: the Combined Response Index for Systemic Sclerosis (CRISS) and Outcome Measures in Pulmonary Arterial Hypertension related to Systemic Sclerosis (EPOSS).
Dinesh Khanna,Oliver Distler,Jérôme Avouac,Frank Behrens,Philip J. Clements,Christopher P. Denton,Ivan Foeldvari,Edward H. Giannini,Doerte Huscher,Otylia Kowal-Bielecka,Daniel J. Lovell,Marco Matucci-Cerinic,Maureen D. Mayes,Peter A. Merkel,Peter Nash,Christian Opitz,David Pittrow,Lewis J. Rubin,James R. Seibold,Virginia D. Steen,C. Vibeke Strand,Peter Tugwell,John Varga,Angela Zink,Daniel E. Furst +24 more
TL;DR: CRISS and EPOSS are being developed through the OMERACT process, significant progress has been made for both indices, and prospective data is being collected.
Journal ArticleDOI
Echocardiography as an Outcome Measure in Scleroderma-related Pulmonary Arterial Hypertension: A Systematic Literature Analysis by the EPOSS Group
Otylia Kowal-Bielecka,Jérôme Avouac,David Pittrow,Doerte Huscher,Frank Behrens,Christopher P. Denton,Ivan Foeldvari,Marc Humbert,Marco Matucci-Cerinic,Peter Nash,Christian Opitz,Lewis J. Rubin,James R. Seibold,Vibeke Strand,Daniel E. Furst,Oliver Distler +15 more
TL;DR: Echocardiography with continuous Doppler was found to lack specificity (lack of content validity), since measurements of echo pulmonary pressure may be influenced by left-heart disease and interstitial lung disease, and further studies are needed to fully validate echo-Doppler as an outcome measure in PAH-SSc.