O
Otylia Kowal-Bielecka
Researcher at Medical University of Białystok
Publications - 117
Citations - 10847
Otylia Kowal-Bielecka is an academic researcher from Medical University of Białystok. The author has contributed to research in topics: Interstitial lung disease & Scleroderma. The author has an hindex of 32, co-authored 111 publications receiving 8846 citations. Previous affiliations of Otylia Kowal-Bielecka include University of Zurich.
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Journal ArticleDOI
Diminished production of TWEAK by the peripheral blood mononuclear cells is associated with vascular involvement in patients with systemic sclerosis.
Marek Bielecki,Krzysztof Kowal,A. Lapinska,Justyna Chwiećko,Jan Skowroński,Stanisław Sierakowski,Lech Chyczewski,Otylia Kowal-Bielecka +7 more
TL;DR: Production of TWEAK by PBMC was significantly diminished in patients with more severe microvascular damage, as indicated by the presence of "active" capillaroscopic pattern, compared with SSc patients with less pronounced microangiopathy ("slow" pattern), and healthy subjects.
Journal ArticleDOI
The role of leukotrienes in the pathogenesis of systemic sclerosis
TL;DR: Blockade of leukotriene pathways appears to be a new, promising target for the treatment of SSc, a autoimmune disease characterized by widespread vascular injury and progressive fibrosis of the skin and internal organs.
Journal ArticleDOI
What have multicentre registries across the world taught us about the disease features of systemic sclerosis
Susanna Proudman,Molla Huq,Wendy Stevens,Michelle Wilson,Joanne Sahhar,Murray Baron,Marie Hudson,Janet E. Pope,Yannick Allanore,Oliver Distler,Otylia Kowal-Bielecka,Marco Matucci-Cerinic,Andrea Hsiu Ling Low,Gim Gee Teng,Weng Giap Law,Amelia Santosa,Mandana Nikpour +16 more
TL;DR: This meta-cohort of SSc patients, the largest reported to date, provides insights into the impact of race and sex on disease manifestations and survival and confirms the early mortality in this disease.
Journal ArticleDOI
A comprehensive framework for navigating patient care in systemic sclerosis: A global response to the need for improving the practice of diagnostic and preventive strategies in SSc.
Lesley Ann Saketkoo,Tracy Frech,Cecília Varjú,Robyn T. Domsic,Jessica Farrell,Jessica K. Gordon,Carina Mihai,Nora Sandorfi,Lee Shapiro,Janet L. Poole,Elizabeth R. Volkmann,Monika Lammi,Kendra McAnally,Helene Alexanderson,Henrik Pettersson,Faye N. Hant,Masataka Kuwana,Ami A. Shah,Vanessa Smith,Vivien Hsu,Otylia Kowal-Bielecka,Shervin Assassi,Maurizio Cutolo,Cristiane Kayser,Victoria K. Shanmugam,Madelon C. Vonk,Kim Fligelstone,Nancy Baldwin,Kerri Connolly,Anneliese Ronnow,Beata Toth,Maureen Suave,Sue Farrington,Elana J. Bernstein,Leslie J. Crofford,László Czirják,Kelly Jensen,Monique Hinchclif,Marie Hudson,Matthew R. Lammi,Jennifer Mansour,Nadia D. Morgan,Fabian A. Mendoza,Mandana Nikpour,John Pauling,Gabriela Riemekasten,Anne-Marie Russell,Mary Beth Scholand,Elise Seigart,Tatiana Sofia Rodriguez-Reyna,Laura K. Hummers,Ulrich A. Walker,Virginia D. Steen +52 more
TL;DR: In this article, the authors present a practical framework with tools to facilitate an optimal, comprehensive and sustainable approach to systemic sclerosis care by sharing care between recognized SSc centers and local cardiology/pulmonary/rheumatology/gastroenterology colleagues.
Journal ArticleDOI
The arachidonate 5-lipoxygenase activating protein gene polymorphism is associated with the risk of scleroderma-related interstitial lung disease: A multicentre European Scleroderma Trials and Research group (EUSTAR) study
Otylia Kowal-Bielecka,Sylwia Chwiesko-Minarowska,Pawel Bernatowicz,Yannick Allanore,Timothy R D J Radstake,Marco Matucci-Cerinic,Jasper C A Broen,Roger Hesselstrand,Dorota Krasowska,G. Riemekasten,Madelon C. Vonk,Oksana Kowalczuk,Marek Bielecki,Robert Milewski,Lech Chyczewski,Jacek Niklinski,Krzysztof Kowal +16 more
TL;DR: The results of this study indicate that the genetic variants of ALOX5AP might play a role in the development of SSc-related pulmonary fibrosis.