O
Oxana Bereshchenko
Researcher at University of Perugia
Publications - 40
Citations - 1295
Oxana Bereshchenko is an academic researcher from University of Perugia. The author has contributed to research in topics: Inflammation & Cellular differentiation. The author has an hindex of 17, co-authored 39 publications receiving 1010 citations. Previous affiliations of Oxana Bereshchenko include Public Health Research Institute & European Bioinformatics Institute.
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Journal ArticleDOI
Glucocorticoids, Sex Hormones, and Immunity.
TL;DR: In this article, similarities and differences between the effects of sex hormones and synthetic glucocorticoids on the immune system are discussed to highlight possible axes of functional interaction, and the link between GCs and sex hormones may exist.
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Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML.
Oxana Bereshchenko,Elena Mancini,Susan J. Moore,Daniel Bilbao,Robert Månsson,Sidinh Luc,Amit Grover,Sten Eirik W. Jacobsen,David Bryder,Claus Nerlov,Claus Nerlov +10 more
TL;DR: The combination of N- and C-terminal C/EBPalpha mutations incorporates both features, accelerating disease development and explaining the clinical prevalence of this configuration of CEBPA mutations in human acute myeloid leukemia.
Journal ArticleDOI
GILZ Promotes Production of Peripherally Induced Treg Cells and Mediates the Crosstalk between Glucocorticoids and TGF-β Signaling
Oxana Bereshchenko,Maddalena Coppo,Stefano Bruscoli,Michele Biagioli,M Cimino,Tiziana Frammartino,Daniele Sorcini,Alessandra Venanzi,Moises Di Sante,Carlo Riccardi +9 more
TL;DR: It is reported that glucocorticoid-induced leucine zipper (GILZ), a protein induced by GCs, promotes Treg cell production and establishes an essential GILZ-mediated link between the anti-inflammatory action of GCs and the regulation of TGF-β-dependent pTreg production.
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A mast cell-ILC2-Th9 pathway promotes lung inflammation in cystic fibrosis
Silvia Moretti,Giorgia Renga,Vasilis Oikonomou,Claudia Galosi,Marilena Pariano,Rossana G. Iannitti,Monica Borghi,Matteo Puccetti,Marco De Zuani,Carlo Pucillo,Giuseppe Paolicelli,Teresa Zelante,Jean-Christophe Renauld,Oxana Bereshchenko,Paolo Sportoletti,Vincenzina Lucidi,Maria Chiara Russo,Carla Colombo,Ersilia Fiscarelli,Cornelia Lass-Flörl,Fabio Majo,Gabriella Ricciotti,Helmut Ellemunter,Luigi Ratclif,Vincenzo Nicola Talesa,Valerio Napolioni,Luigina Romani +26 more
TL;DR: It is shown that IL-9 increases IL-2 production by mast cells, which leads to expansion of CD25+ type 2 innate lymphoid cells (ILC2) and subsequent activation of Th9 cells, and blocking IL-7 or inhibiting CD117 (c-Kit) signalling counteracts the pathogenic effect of the described IL- 9-mast cell-IL-2 signalling axis.
Journal ArticleDOI
Swing-Gate Model of Nucleotide Entry into the RNA Polymerase Active Center
Vitaliy Epshtein,Vitaliy Epshtein,Arkady Mustaev,Vadim Markovtsov,Oxana Bereshchenko,Vadim Nikiforov,Vadim Nikiforov,Alex Goldfarb +7 more
TL;DR: Each elementary step of transcription involves translocation of the 3' terminus of RNA in the RNA polymerase active center, followed by the entry of a nucleoside triphosphate, and the structural basis of these transitions was studied using RNA-protein crosslinks.