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Carla Colombo
Researcher at Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Publications - 285
Citations - 8223
Carla Colombo is an academic researcher from Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico. The author has contributed to research in topics: Cystic fibrosis & Liver disease. The author has an hindex of 43, co-authored 267 publications receiving 6758 citations. Previous affiliations of Carla Colombo include University of Milan & Free University of Berlin.
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Journal ArticleDOI
ESPEN-ESPGHAN-ECFS guidelines on nutrition care for infants, children, and adults with cystic fibrosis
Dominique Turck,Christian Braegger,Carla Colombo,Dimitri Declercq,Alison Morton,Ruzha Pancheva,Eddy Robberecht,Martin Stern,Birgitta Strandvik,Sue Wolfe,Stéphane M. Schneider,Michael Wilschanski +11 more
TL;DR: Nutritional care and support should be an integral part of management of CF, and obtaining a normal growth pattern in children and maintaining an adequate nutritional status in adults are major goals of multidisciplinary cystic fibrosis centers.
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Best practice guidance for the diagnosis and management of cystic fibrosis-associated liver disease
TL;DR: All CF patients with liver disease need annual follow-up to evaluate the development of cirrhosis, portal hypertension or liver failure, particularly in children with hepatic dysfunction or advanced portal hypertension.
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Genetic modifiers of liver disease in cystic fibrosis.
Jaclyn R. Bartlett,Kenneth J. Friedman,Simon C. Ling,Rhonda G. Pace,Scott C. Bell,Billy Bourke,Giuseppe Castaldo,Carlo Castellani,Marco Cipolli,Carla Colombo,John L. Colombo,Dominique Debray,Adriana Fernandez,F. Lacaille,Milan Macek,Marion Rowland,Marion Rowland,Francesco Salvatore,Christopher J. Taylor,Claire E. Wainwright,Michael Wilschanski,Dana Zemkova,William B. Hannah,M. James Phillips,Mary Corey,Julian Zielenski,Ruslan Dorfman,Yunfei Wang,Fei Zou,Lawrence M. Silverman,Mitchell L. Drumm,Fred A. Wright,Ethan M. Lange,Peter R. Durie,Michael R. Knowles +34 more
TL;DR: The SERPINA1 Z allele is a risk factor for liver disease in CF and patients who carry the Z allele are at greater risk of developing severe liver disease with portal hypertension.
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Ursodeoxycholic Acid for Liver Disease Associated With Cystic Fibrosis: A Double-Blind Multicenter Trial
TL;DR: It is concluded that UDCA administration improves clinical and biochemical parameters in CF patients with liver disease and taurine supplementation may be indicated in patients with severe pancreatic insufficiency and poor nutritional status.
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IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis
Rossana G. Iannitti,Valerio Napolioni,Vasilis Oikonomou,Antonella De Luca,Claudia Galosi,Marilena Pariano,Cristina Massi-Benedetti,Monica Borghi,Matteo Puccetti,Vincenzina Lucidi,Carla Colombo,Ersilia Fiscarelli,Cornelia Lass-Flörl,Fabio Majo,Lisa Cariani,Maria Chiara Russo,Luigi Porcaro,Gabriella Ricciotti,Helmut Ellemunter,Luigi Ratclif,Fernando Maria de Benedictis,Vincenzo Nicola Talesa,Charles A. Dinarello,Frank L. van de Veerdonk,Luigina Romani +24 more
TL;DR: Results indicate that pathogenic NLRP3 activity in CF could be negatively regulated by IL-1Ra and provide a proof-of-concept evidence that inflammasomes are potential targets to limit the pathological consequences of microbial colonization in CF.