P
P. Andrew Futreal
Researcher at University of Texas at Austin
Publications - 32
Citations - 11582
P. Andrew Futreal is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Breast cancer & Tumor suppressor gene. The author has an hindex of 18, co-authored 32 publications receiving 10098 citations. Previous affiliations of P. Andrew Futreal include Howard Hughes Medical Institute & Wellcome Trust.
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Supplementary file 2.
Young Seok Ju,Ludmil B. Alexandrov,Moritz Gerstung,Inigo Martincorena,Serena Nik-Zainal,Manasa Ramakrishna,Helen Davies,Elli Papaemmanuil,Gunes Gundem,Adam Shlien,Niccolo Bolli,Sam Behjati,P. S. Tarpey,Jyoti Nangalia,Charles E. Massie,Adam P. Butler,Jon W. Teague,George S. Vassiliou,Anthony R. Green,Ming-Qing Du,Ashwin Unnikrishnan,John E. Pimanda,Bin Tean Teh,Nikhil C. Munshi,Mel Greaves,Paresh Vyas,Adel K. El Naggar,Tom Santarius,V. Peter Collins,Richard Grundy,Jack A. Taylor,D. Neil Hayes,David Malkin,Christopher S. Foster,Anne Y. Warren,Hayley C. Whitaker,Daniel Brewer,Rosalind Eeles,Colin Cooper,David E. Neal,T. Visakorpi,W. Isaacs,G. Steven Bova,Adrienne M. Flanagan,P. Andrew Futreal,Andy G. Lynch,Patrick F. Chinnery,Ultan McDermott,Michael R. Stratton,Peter J. Campbell +49 more
TL;DR: Predictor OR (95% CI) P value Day/time of arrest (vs Weekday daytime) <0.001 Weekend daytime 0.72 (0.64, 0.80) Night-time 0.58 (0."54,0.63) Age (restricted cubic splines)* 0.761 ( 0.338, 1.714) Prior length of stay (vs 0 days) < 0.001
Patent
17q-linked breast cancer susceptibility gene and ovarian
Mark H. Skolnick,David E Goldgar,Yoshio Miki,Jeff Swensen,Alexander Kamb,Keith D Harshman,Donna M Shattuck-Eidens,Sean V Tavtigian,Roger W Wiseman,P. Andrew Futreal +9 more
Patent
17Q-Linked ovarian and breast cancer susceptibility gene
Mark H. Skolnick,David E Goldgar,Yoshio Miki,Jeff Swensen,Alexander Kamb,Keith D Harshman,Donna M Shattuck-Eidens,Sean V Tavtigian,Roger W Wiseman,P. Andrew Futreal +9 more
COSMIC, curating the cancer variome
TL;DR: The current version of COSMIC is close to fulfilling its original intentions, with curation of most pointmutated genes in cancer complete, however, new challenges are emerging with the need to calculate the effect of high numbers of observed sequence changes to identify those driving tumour formation, and theneed to meaningfully handle the increasing quantities of data from high-throughput screens and next-generation sequencing technologies.
Patent
Procede pour diagnostiquer une predisposition au cancer du sein et des ovaires
Mark H. Skolnick,David E Goldgar,Yoshio Miki,Jeff Swenson,Alexander Kamb,Keith D Harshman,Donna M Shattuck-Eidens,Sean V Tavtigian,Roger W Wiseman,P. Andrew Futreal +9 more
TL;DR: The authors concerne des procedes et des materiaux utilises for isoler et detecter un gene humain de predisposition au cancer du sein et des ovaires (BRCA1), don't certains alleles mutants provoquent la sensibilite au cancer, en particulier, au cancer de sein and des ovaires.