P
Pär Jonsson
Researcher at Umeå University
Publications - 43
Citations - 3540
Pär Jonsson is an academic researcher from Umeå University. The author has contributed to research in topics: Chemometrics & Metabolomics. The author has an hindex of 22, co-authored 41 publications receiving 3268 citations. Previous affiliations of Pär Jonsson include Swedish University of Agricultural Sciences & Nanjing Medical University.
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Journal ArticleDOI
Extraction and GC/MS Analysis of the Human Blood Plasma Metabolome
A Jiye,Johan Trygg,Jonas Gullberg,Annika I. Johansson,Pär Jonsson,Henrik Antti,Stefan L. Marklund,Thomas Moritz +7 more
TL;DR: An extraction and derivatization protocol, developed using experimental design theory, for analyzing the human blood plasma metabolome by GC/MS, suggests that the method could be usefully integrated into metabolomic studies for various purposes, e.g., for identifying biological markers related to diseases.
Journal ArticleDOI
Design of experiments: an efficient strategy to identify factors influencing extraction and derivatization of Arabidopsis thaliana samples in metabolomic studies with gas chromatography/mass spectrometry.
TL;DR: The results show that this approach allows a reliable protocol for metabolomic analysis of Arabidopsis to be determined with a relatively limited number of experiments, and it was shown that both hydrophilic and lipophilic compounds were detected with high reproducibility.
Journal ArticleDOI
High-throughput data analysis for detecting and identifying differences between samples in GC/MS-based metabolomic analyses.
Pär Jonsson,Annika I. Johansson,Jonas Gullberg,Johan Trygg,Jiye A,Bjørn Grung,Stefan L. Marklund,Michael Sjöström,and Henrik Antti,Thomas Moritz +9 more
TL;DR: A new semiautomated strategy using a hierarchical multivariate curve resolution approach that processes all samples simultaneously is described that generates tables of all the detected metabolites that differ in relative concentrations between samples.
Journal ArticleDOI
A Strategy for Identifying Differences in Large Series of Metabolomic Samples Analyzed by GC/MS
Pär Jonsson,Jonas Gullberg,Anders Nordström,Miyako Kusano,Mauriusz Kowalczyk,Michael Sjöström,Thomas Moritz +6 more
TL;DR: This method can be used for rapid comparison of large sets of GC/MS data, thereby applying time-consuming deconvolution only to parts of the chromatograms that contribute to explain the differences between the samples.
Journal ArticleDOI
Summary recommendations for standardization and reporting of metabolic analyses.
John C. Lindon,Jeremy K. Nicholson,Elaine Holmes,Hector C. Keun,Andrew Craig,Jake T M Pearce,Stephen J. Bruce,Nigel Hardy,Susanna-Assunta Sansone,Henrik Antti,Pär Jonsson,Clare A. Daykin,Mahendra Navarange,Richard D. Beger,Elwin Verheij,Alexander Amberg,Dorrit Baunsgaard,Glenn H. Cantor,Lois D. Lehman-McKeeman,Mark Earll,Svante Wold,Erik Johansson,John N. Haselden,Kerstin Kramer,Craig E. Thomas,Johann Lindberg,Ina Schuppe-Koistinen,Ian D. Wilson,Michael D. Reily,Donald G. Robertson,Hans Senn,Arno Krotzky,Sunil Kochhar,Jonathan J. Powell,Frans van der Ouderaa,Robert S. Plumb,Hartmut Schaefer,Manfred Spraul +37 more
TL;DR: The Standard Metabolic Reporting Structures (SMRS) working group outlines its vision for an open, community-driven specification for the standardization and reporting of metabolic studies.