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Patricia Ohrmann

Researcher at University of Münster

Publications -  94
Citations -  6532

Patricia Ohrmann is an academic researcher from University of Münster. The author has contributed to research in topics: Schizophrenia & Facial expression. The author has an hindex of 44, co-authored 91 publications receiving 5989 citations.

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Automatic mood-congruent amygdala responses to masked facial expressions in major depression.

TL;DR: Depressed patients exhibit potentiated amygdala reactivity to masked negative stimuli along with a reduced responsiveness to masked positive stimuli compared with healthy individuals, indicating that depression is characterized by mood-congruent processing of emotional stimuli in the amygdala already at an automatic level of processing.
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Effective electroconvulsive therapy reverses glutamate/glutamine deficit in the left anterior cingulum of unipolar depressed patients

TL;DR: Severe depression seems to be associated with a Glx deficit and increasing Glx may be an important mechanism of ECT action, and in ECT responders, in contrast to non-responders, Glx levels normalized and then did not differ statistically from controls.
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Metabolic changes within the left dorsolateral prefrontal cortex occurring with electroconvulsive therapy in patients with treatment resistant unipolar depression.

TL;DR: The results indicate that major depressive disorder is accompanied by state-dependent metabolic alterations, especially in glutamate/glutamine metabolism, which can be reversed by successful ECT.