Harald Kugel

TL;DR: The present results might suggest that limbic hyperresponsiveness and reduced hippocampal volumes could be mediators between the experiences of adversities during childhood and the development of emotional disorders.

TL;DR: In this article, the authors present the largest ever worldwide study by the ENIGMA (Enhancing Neuro Imaging Genetics through Meta-Analysis) Major Depressive Disorder Working Group on cortical structural alterations in MDD.

TL;DR: The largest study to date of cortical gray matter thickness and surface area measures from brain magnetic resonance imaging scans of bipolar disorder patients is performed, revealing previously undetected associations and providing an extensive analysis of potential confounding variables in neuroimaging studies of BD.

TL;DR: Depressed patients exhibit potentiated amygdala reactivity to masked negative stimuli along with a reduced responsiveness to masked positive stimuli compared with healthy individuals, indicating that depression is characterized by mood-congruent processing of emotional stimuli in the amygdala already at an automatic level of processing.

TL;DR: The authors revealed a nonlinear winner‐take‐all effect for a participant's favorite brand characterized, on one hand, by reduced activation in brain areas associated with working memory and reasoning and, on the other hand, increased activation in areas involved in processing of emotions and self‐reflections during decision making.