P
Patrick C. Y. Woo
Researcher at Li Ka Shing Faculty of Medicine, University of Hong Kong
Publications - 621
Citations - 37320
Patrick C. Y. Woo is an academic researcher from Li Ka Shing Faculty of Medicine, University of Hong Kong. The author has contributed to research in topics: Coronavirus & Gene. The author has an hindex of 85, co-authored 593 publications receiving 31877 citations. Previous affiliations of Patrick C. Y. Woo include The Chinese University of Hong Kong & Kwong Wah Hospital.
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Journal ArticleDOI
Identification of specific metabolites in culture supernatant of Mycobacterium tuberculosis using metabolomics: exploration of potential biomarkers
Susanna K. P. Lau,Ching-Wan Lam,Shirly O. T. Curreem,Kim Chung Lee,Candy C. Y. Lau,Wang Ngai Chow,Antonio H. Y. Ngan,Kelvin K. W. To,Jasper Fuk-Woo Chan,Ivan Hung,Wing-Cheong Yam,Kwok-Yung Yuen,Patrick C. Y. Woo +12 more
TL;DR: This work characterized the extracellular metabolomes of culture supernatant of nine MTB strains and nine non-tuberculous Mycobacterium (NTM) strains using an optimized ultrahigh performance liquid chromatography–electrospray ionization–quadruple time of flight–mass spectrometry platform.
Journal ArticleDOI
Internal transcribed spacer region sequence heterogeneity in Rhizopus microsporus: implications for molecular diagnosis in clinical microbiology laboratories.
Patrick C. Y. Woo,Shui-Yee Leung,Kelvin K. W. To,Jasper Fuk-Woo Chan,Antonio H. Y. Ngan,Vincent C.C. Cheng,Susanna K. P. Lau,Kwok-Yung Yuen +7 more
TL;DR: Evidence of internal transcribed spacer region (ITS) sequence heterogeneity in Mucorales is presented for the first time, in a recent outbreak investigation of intestinal mucormycosis due to Rhizopus microsporus infection in patients with hematological malignancies.
Journal ArticleDOI
Antibiotics create a shift from mutualism to competition in human gut communities with a longer-lasting impact on fungi than bacteria.
Bastian Seelbinder,Jiarui Chen,Jiarui Chen,Sascha Brunke,Ruben Vazquez-Uribe,Rakesh Santhaman,Anne-Christin Meyer,Felipe Senne de Oliveira Lino,Ka-Fai Chan,Daniel Loos,Lejla Imamovic,Chi-Ching Tsang,Rex Pui Kin Lam,Siddharth Sridhar,Siddharth Sridhar,Kang Kang,Bernhard Hube,Patrick C. Y. Woo,Patrick C. Y. Woo,Morten Otto Alexander Sommer,Gianni Panagiotou,Gianni Panagiotou +21 more
TL;DR: It is demonstrated that antibacterial drugs have long-term influence on the human gut mycobiome and bacterial strains inhibiting the opportunistic fungal pathogen Candida albicans are revealed by extending the metagenomic species approach.
Journal ArticleDOI
Synthetic peptides outside the spike protein heptad repeat regions as potent inhibitors of SARS-associated coronavirus.
Bo-Jion Zheng,Yi Guan,Ming-Liang Hez,Hongzhe Sun,Lanying Du,Ying Zheng,Kin-Ling Wong,Honglin Chen,Ying Chen,Lin Yu Lu,Julian A. Tanner,Rory M. Watt,Neri Niccolai,Andrea Bernini,Ottavia Spiga,Patrick C. Y. Woo,Hsiang-Fu Kung,Kwok-Yung Yuen,Jian-Dong Huang +18 more
TL;DR: These results revealed novel regions in the spike protein that can be targeted to inhibit viral infection, and could be further developed into antiviral drugs.
Journal ArticleDOI
Tuberculosis in blood and marrow transplant recipients.
Kwok-Yung Yuen,Patrick C. Y. Woo +1 more
TL;DR: The absence of relapse after termination of treatment in patients suggested that secondary prophylaxis would not be necessary as long as immune function has been restored, and it is important to bear a high index of suspicion of Mycobacterium tuberculosis as a pathogen in BMT recipients.