Patrick C. Y. Woo

TL;DR: The biophysical, biochemical and structural characterization of recombinant LHK-Exo protein is reported, and a conserved two metal ion catalytic mechanism is proposed for this class of alkaline exonucleases.

TL;DR: An empirical analysis of the publication trends suggests continuing interests in novel diagnostics, fungal pathogenesis, review of clinical diseases especially with relevance to the laboratory scientists, taxonomy and classification of fungal pathogens,fungal infections and carriage in pets and wildlife, and changing ecology and epidemiology offungal diseases around the globe.

TL;DR: The risk of fungal infection in patients receiving cytokine antagonists and immune checkpoint inhibitors, two big categories of biologic agents that are widely used in the treatment of various autoimmune and malignant conditions, is highlighted.

TL;DR: In patients with stable SLE not receiving intensive immunosuppression, Zostavax was well-tolerated and provoked an immune response.

TL;DR: Although matrix-assisted laser desorption ionisation-time-of-flight mass spectrometry is an emerging technology for bacterial identification in clinical laboratories, it is not feasible to manually interpret the raw data in case of ambiguous results, so gene sequencing or a polyphasic approach for bacterial Identification is still the standard to resolve difficult cases.