P
Paul Dremsek
Researcher at Friedrich Loeffler Institute
Publications - 12
Citations - 924
Paul Dremsek is an academic researcher from Friedrich Loeffler Institute. The author has contributed to research in topics: Hepatitis E virus & Seroprevalence. The author has an hindex of 11, co-authored 12 publications receiving 807 citations.
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Journal ArticleDOI
Different Outcomes of Experimental Hepatitis E Virus Infection in Diverse Mouse Strains, Wistar Rats, and Rabbits.
Josephine Schlosser,Lisa Dähnert,Paul Dremsek,Kerstin Tauscher,Christine Fast,Ute Ziegler,Albrecht Gröner,Rainer G. Ulrich,Martin H. Groschup,Martin Eiden +9 more
TL;DR: The rabbit model for HEV-3 infection may serve as a suitable alternative to the non-human primate and swine models, and as an appropriate basis for vaccine evaluation studies.
Journal ArticleDOI
Seroprevalence study in forestry workers from eastern Germany using novel genotype 3- and rat hepatitis E virus-specific immunoglobulin G ELISAs
Paul Dremsek,Jürgen J. Wenzel,Reimar Johne,Mario Ziller,Jörg Hofmann,Martin H. Groschup,Sandra Werdermann,Ulrich Mohn,Silvia Dorn,Manfred Motz,Marc Mertens,Wolfgang Jilg,Rainer G. Ulrich +12 more
TL;DR: Four Escherichia coli-expressed segments of the capsid protein of a German wild boar-derived HEV genotype 3 strain were tested for their diagnostic value in an indirect immunoglobulin G (IgG) ELISA and an indirect ELISA for detection of anti-HEV IgG antibodies in human sera was established and validated.
Journal ArticleDOI
Hepeviridae: an expanding family of vertebrate viruses.
TL;DR: A suggestion for a new taxonomic grouping scheme of the viruses within the family Hepeviridae is presented, and a distantly related agent was described from closely related salmonid fish.
Journal ArticleDOI
Rat hepatitis E virus: geographical clustering within Germany and serological detection in wild Norway rats (Rattus norvegicus).
Reimar Johne,Paul Dremsek,Eveline Kindler,Anika Schielke,Anika Schielke,A. Plenge-Bönig,Henrike Gregersen,Ute Wessels,Katja Schmidt,Wolfram Rietschel,Martin H. Groschup,Sebastian Guenther,Gerald Heckel,Gerald Heckel,Rainer G. Ulrich +14 more
TL;DR: The present data indicated a continuing existence of this virus in the rat populations from Berlin and Hamburg, and the recombinant ratHEV antigen generated here will allow future seroepidemiological studies to differentiateRatHEV and genotype 3 infections in humans and animals.
Journal ArticleDOI
Natural and experimental hepatitis E virus genotype 3 - infection in European wild boar is transmissible to domestic pigs
Josephine Schlosser,Martin Eiden,Ariel Vina-Rodriguez,Christine Fast,Paul Dremsek,Elke Lange,Rainer G. Ulrich,Martin H. Groschup +7 more
TL;DR: Given the high virus loads and long duration of viral shedding, wild boar has to be considered as an important HEV reservoir and transmission host in Europe.