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Paul G. Braunschweiger
Researcher at University of Miami
Publications - 49
Citations - 1898
Paul G. Braunschweiger is an academic researcher from University of Miami. The author has contributed to research in topics: Cytotoxicity & Clonogenic assay. The author has an hindex of 23, co-authored 49 publications receiving 1836 citations.
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Journal ArticleDOI
2-Deoxy-d-glucose Increases the Efficacy of Adriamycin and Paclitaxel in Human Osteosarcoma and Non-Small Cell Lung Cancers In Vivo
Gregory Maschek,Niramol Savaraj,Waldemar Priebe,Paul G. Braunschweiger,Kara Hamilton,George F. Tidmarsh,Linda R. De Young,Theodore J. Lampidis +7 more
TL;DR: Treatment of tumors with both the glycolytic inhibitor 2-DG and ADR or paclitaxel results in a significant reduction in tumor growth compared with either agent alone, providing a rationale for initiating clinical trials using glyCOlytic inhibitors in combination with chemotherapeutic agents to increase their therapeutic effectiveness.
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NMR study of in vivo RIF-1 tumors: Analysis of perchloric acid extracts and identification of 1H, 31P and 13C resonances
William T. Evanochko,Ted T. Sakai,Thian C. Ng,N. Rama Krishna,Hyun Dju Kim,Robert B. Zeidler,Vithal K. Ghanta,R. Wallace Brockman,Lewis M. Schiffer,Paul G. Braunschweiger,Jerry D. Glickson +10 more
TL;DR: Perchloric acid extracts of radiation-induced fibrosarcoma (RIF-1) tumors grown in mice have been analyzed by multinuclear NMR spectroscopy and by various chromatographic methods, allowing the unambiguous assignment of the 31P resonances observed in vivo to specific phosphorus-containing metabolites.
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In vivo hematopoietic effects of recombinant interleukin-1 alpha in mice: stimulation of granulocytic, monocytic, megakaryocytic, and early erythroid progenitors, suppression of late-stage erythropoiesis, and reversal of erythroid suppression with erythropoietin.
Candace S. Johnson,Douglas J. Keckler,Maureen I. Topper,Paul G. Braunschweiger,Philip Furmanski +4 more
TL;DR: The potential use of IL-1 alpha as a generalized stimulator of hematopoiesis is demonstrated and it is shown that the cytokine- induced suppression of late-stage erythropoiedis can be prevented by EPO.
Journal ArticleDOI
The CITI program: an international online resource for education in human subjects protection and the responsible conduct of research.
TL;DR: It is submitted that when all members of the team are educated about common moral standards and appropriately mentored, the temptation for misbehavior by any one member is reduced, better science is promoted, and the public trust is preserved.
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A carbohydrate-linked cisplatin analogue having antitumor activity
TL;DR: An unprotected and intact carbohydrate moiety has been observed for the first time in a transition metal complex, and exhibits comparable antitumor activity along with increased solubility in water.