T
Theodore J. Lampidis
Researcher at University of Miami
Publications - 99
Citations - 5462
Theodore J. Lampidis is an academic researcher from University of Miami. The author has contributed to research in topics: Rhodamine 123 & Cell culture. The author has an hindex of 36, co-authored 96 publications receiving 5139 citations. Previous affiliations of Theodore J. Lampidis include University of Texas Health Science Center at Houston & Harvard University.
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Journal ArticleDOI
2-Deoxy-d-glucose Increases the Efficacy of Adriamycin and Paclitaxel in Human Osteosarcoma and Non-Small Cell Lung Cancers In Vivo
Gregory Maschek,Niramol Savaraj,Waldemar Priebe,Paul G. Braunschweiger,Kara Hamilton,George F. Tidmarsh,Linda R. De Young,Theodore J. Lampidis +7 more
TL;DR: Treatment of tumors with both the glycolytic inhibitor 2-DG and ADR or paclitaxel results in a significant reduction in tumor growth compared with either agent alone, providing a rationale for initiating clinical trials using glyCOlytic inhibitors in combination with chemotherapeutic agents to increase their therapeutic effectiveness.
Journal ArticleDOI
Mitochondrial and plasma membrane potentials cause unusual accumulation and retention of rhodamine 123 by human breast adenocarcinoma-derived MCF-7 cells.
TL;DR: Quantitative studies of MCF-7 cells and CV-1 cells using the permeant cationic compound tetraphenylphosphonium, in conjunction with fluorescence microscopy using rhodamine 123 (Rh123), indicate that the mitochondrial and plasma membrane potentials affect both uptake and retention of these compounds.
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Unusual retention of rhodamine 123 by mitochondria in muscle and carcinoma cells.
Ian C. Summerhayes,Theodore J. Lampidis,Samuel D. Bernal,John J. Nadakavukaren,Karen K. Nadakavukaren,Elizabeth L. Shepherd,Lan Bo Chen +6 more
TL;DR: Mitochondria in cardiac muscle cells and myoblast-fused myotubes display unusually long retention times of rhodamine 123, a mitochondria-specific fluorescent probe, in living cells, and the presence of mitochondria having unusual dye retention may be useful for diagnosis and exploitable for chemotherapy of certain human carcinomas.
Journal Article
Selective Toxicity of Rhodamine 123 in Carcinoma Cells in Vitro
TL;DR: It is demonstrated that with continuous exposure, rhodamine 123 selectively kills carcinoma as compared to normal epithelial cells grown in vitro.
Journal ArticleDOI
Anticarcinoma activity in vivo of rhodamine 123, a mitochondrial-specific dye
TL;DR: Carcinoma cells and normal epithelial cells differ in the mitochondrial retention of a permeant cationic compound, rhodamine 123, and this difference in carcinoma chemotherapy was investigated.