P
Paul H. Gibbs
Researcher at United States Army Medical Research Institute of Infectious Diseases
Publications - 39
Citations - 3613
Paul H. Gibbs is an academic researcher from United States Army Medical Research Institute of Infectious Diseases. The author has contributed to research in topics: Anthrax vaccines & Vaccination. The author has an hindex of 31, co-authored 39 publications receiving 3461 citations. Previous affiliations of Paul H. Gibbs include United States Department of the Army.
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Journal ArticleDOI
Prospective, Double-Blind, Concurrent, Placebo-Controlled Clinical Trial of Intravenous Ribavirin Therapy of Hemorrhagic Fever with Renal Syndrome
John W. Huggins,Chin Min Hsiang,Thomas M. Cosgriff,Mei Ying Guang,Joseph I. Smith,Zhen Ou Wu,James W. LeDuc,Zhi-Ming Zheng,J M Meegan,Qi Nan Wang,Dwayne D. Oland,Xi En Gui,Paul H. Gibbs,Guang Hui Yuan,Tian Ming Zhang +14 more
TL;DR: Ribavirin therapy resulted in a significant reduction in the risk of entering the oliguric phase and experiencing hemorrhage, and the only ribavirin-related side effect was a well-recognized, fully reversible anemia after completion of therapy.
Journal ArticleDOI
Differences in susceptibility of inbred mice to Bacillus anthracis.
TL;DR: The mouse model appears to be useful in studies on host resistance to anthrax and on the pathogenesis of the infection, especially when studies suggested that resistance to the Sterne strain is determined by a single dominant gene or gene complex.
Journal ArticleDOI
In vitro correlate of immunity in a rabbit model of inhalational anthrax.
Margaret L. Pitt,Stephen F. Little,Bruce E. Ivins,P.F. Fellows,J. Barth,John Hewetson,Paul H. Gibbs,Mark T. Dertzbaugh,Arthur M. Friedlander +8 more
TL;DR: A serological correlate of vaccine-induced immunity was identified in the rabbit model of inhalational anthrax and antibody levels to PA at both 6 and 10 weeks were significant predictors of survival.
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Comparative efficacy of experimental anthrax vaccine candidates against inhalation anthrax in rhesus macaques.
Bruce E. Ivins,Margaret L. Pitt,P.F. Fellows,Joseph Farchaus,G. E. Benner,David M. Waag,Stephen F. Little,G.W. Anderson,Paul H. Gibbs,Arthur M. Friedlander +9 more
TL;DR: The authors examined the efficacy of Bacillus anthracis protective antigen (PA) combined with adjuvants as vaccines against an aerosol challenge of virulent anthrax spores in rhesus macaques.
Journal ArticleDOI
Protective Efficacy of a Live Attenuated Vaccine against Argentine Hemorrhagic Fever
Julio I. Maiztegui,Kelly T. McKee,Julio G. Barrera Oro,Lee H. Harrison,Paul H. Gibbs,María R. Feuillade,Delia Enria,Ana M. Briggiler,Silvana Levis,Ana M. Ambrosio,Neal A. Halsey,Clarence J. Peters +11 more
TL;DR: Candid 1, the first vaccine for the prevention of illness caused by an arenavirus, is safe and highly efficacious and no serious adverse events were attributed to vaccination.