Paul J. Reier

TL;DR: Fetal rat spinal cord tissue was obtained on gestational day 14 and transplanted into 2–4‐mm‐long intraspinal cavities produced by partial spinal cord lesions in adult and neonatal rats to identify surviving donor tissues and to study their differentiation and extent of fusion with recipient spinal cords.

TL;DR: Spinal cord transplants prevented the massive retrograde cell death of immature axotomized rubrospinal neurons and the number of neurons in animals with lesions and transplants was not significantly different from control animals.

TL;DR: The results of this study suggest that some topographical features of the normal spinal cord may be represented in mature spinal cord transplants, and establish a basis for future investigations aimed at repair of the injured host spinal cord with homologous fetal tissue.

TL;DR: Observations suggest that microtubules are involved in the initial establishment of cytoplasmic asymmetry and process development, and glial filaments may play a role in maintaining and stabilizing the overall geometry of the mature astrocyte.

TL;DR: Observations provide additional evidence emphasizing the importance of the ependymal cell surface during axonal outgrowth in the regenerating spinal cord, as opposed to previous reports, which focused on the formation of pre-existing ependyma channels.