P
Paulo Humberto Moreira Nunes
Researcher at Federal University of Piauí
Publications - 22
Citations - 267
Paulo Humberto Moreira Nunes is an academic researcher from Federal University of Piauí. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 8, co-authored 17 publications receiving 191 citations. Previous affiliations of Paulo Humberto Moreira Nunes include Universal Forest Products.
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Journal ArticleDOI
Gastroprotective activity of carvacrol on experimentally induced gastric lesions in rodents
Irisdalva S. Oliveira,Francilene V. Silva,Ana Flávia Seraine Custódio Viana,Márcio R. V. Santos,Lucindo José Quintans-Júnior,Maria do Carmo de Carvalho e Martins,Paulo Humberto Moreira Nunes,Francisco Rodrigo de Asevedo Mendes de Oliveira,Rita de Cássia Meneses Oliveira +8 more
TL;DR: It is demonstrated that carvacrol promoted a marked gastroprotection in all models investigated, possibly mediated by endogenous prostaglandins, increase of mucus production, KATP channels opening, NO synthase activation, and antioxidant properties.
Journal ArticleDOI
Antibacterial, antibiofilm and cytotoxic activities of Terminalia fagifolia Mart. extract and fractions
Alyne Rodrigues de Araújo,Patrick Veras Quelemes,Márcia Luana Gomes Perfeito,Luiza Ianny de Lima,Luiza Ianny de Lima,Melka Coelho Sá,Paulo Humberto Moreira Nunes,Graziella Anselmo Joanitti,Peter Eaton,Maria José dos Santos Soares,José Roberto S. A. Leite +10 more
TL;DR: Both the EtE and fractions showed a moderate cytotoxicity in cell line NIH/3T3 viability and potential antitumoral activity on human breast cancer cell line MCF-7, and both showed significant inhibition of the biofilm formation, with inhibition of biofilms formation of over 80% for some strains.
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Antiulcer activity of ethanolic extract of Encholirium spectabile Mart. ex Schult & Schult f. (Bromeliaceae) in rodents
Katharinne I Moraes de Carvalho,Hélio B Fernandes,Flávia Danniele Frota Machado,Irisdalva S. Oliveira,Francisco Artur Forte Oliveira,Paulo Humberto Moreira Nunes,Julianeli Tolentino de Lima,Jackson Roberto Guedes da Silva Almeida,Rita de Cássia Meneses Oliveira +8 more
TL;DR: ES-EtOH protected the gastric mucosa against ulceration that was induced by absolute ethanol, ethanol/HCl, ibuprofen and ischemia/reperfusion, which indicates that prostaglandins, antioxidant compounds and nitric oxide synthase activity are involved in the gastroprotective activity of the extract.
Journal Article
Antiulcerogenic activity of Combretum leprosum.
Paulo Humberto Moreira Nunes,P. M. S. Cavalcanti,S. M. P. Galvão,Maria do Carmo de Carvalho e Martins +3 more
TL;DR: Evidence is provided that the ethanolic extract of Combretum leprosum possesses gastroprotective and anti-ulcerogenic effects, which are related to the inhibition of the gastric acid secretion and an increase of mucosal defensive factors such as mucus and prostaglandin.
Journal ArticleDOI
Identification of Eschweilenol C in derivative of Terminalia fagifolia Mart. and green synthesis of bioactive and biocompatible silver nanoparticles
Alyne Rodrigues de Araújo,Joilson Ramos-Jesus,Taiane Maria de Oliveira,Andressa Maria Aguiar de Carvalho,Paulo Humberto Moreira Nunes,Tatiane Caroline Daboit,Ana P. Carvalho,M.F. Barroso,Miguel Peixoto de Almeida,Alexandra Plácido,Artur Rodrigues,Camila C. Portugal,Renato Socodato,João B. Relvas,Cristina Delerue-Matos,Durcilene Alves da Silva,Peter Eaton,José Roberto S. A. Leite,José Roberto S. A. Leite +18 more
TL;DR: In this paper, a green synthetic route was developed to prepare silver nanoparticles (AgNPs) in aqueous solution for biological applications, which showed high levels of antioxidant and considerable antibacterial and antifungal activities.