Pedro Sánchez-Godoy

TL;DR: Mortality was associated with higher age, more comorbidities, type of hematological malignancy and type of antineoplastic therapy, and further studies and long-term follow-up are required to validate these criteria for risk stratification.

TL;DR: The data from this exploratory study suggest that the accumulation of molecular events seems to influence the outcome of HL, particularly in the low-IPS group.

TL;DR: FLT3-internal tandem duplication mutations are associated with several hematologic features in acute promyelocytic leukemia, in particular with high white blood cell counts, but it was unable to demonstrate an independent prognostic value in patients treated with all-trans retinoic acid and anthracycline-based regimens.

TL;DR: A multistep approach was taken to design a quantitative reverse-transcription polymerase chain reaction assay to be applied to routine formalin-fixed paraffin-embedded samples, integrating genes expressed by the tumor cells and their microenvironment and able to identify a group of patients with very bad outcome.

TL;DR: In this article, gene expression data from advanced cHL patients were used to identify transcriptional patterns from the tumoral cells and their non-neoplastic microenvironment, associated with lack of maintained treatment response.