P
Pengchao Zhao
Researcher at The Chinese University of Hong Kong
Publications - 24
Citations - 913
Pengchao Zhao is an academic researcher from The Chinese University of Hong Kong. The author has contributed to research in topics: Self-healing hydrogels & Chemistry. The author has an hindex of 10, co-authored 18 publications receiving 440 citations.
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Journal ArticleDOI
Bioadhesive hydrogels demonstrating pH-independent and ultrafast gelation promote gastric ulcer healing in pigs.
Xiayi Xu,Xianfeng Xia,Xianfeng Xia,Kunyu Zhang,Kunyu Zhang,Aliza Rai,Zhuo Li,Pengchao Zhao,Kongchang Wei,Kongchang Wei,Li Zou,Boguang Yang,Wai-Ki Wong,Philip Wai Yan Chiu,Liming Bian +14 more
TL;DR: The development of a hydrogel based on thiourea-catechol reaction to enhance the bioadhesion is reported, showing enhanced mechanical properties, exceedingly short curing time, and pH-independent gelation with a much lower oxidant concentration.
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Organic Semiconducting Polymer Nanoparticles for Photoacoustic Labeling and Tracking of Stem Cells in the Second Near-Infrared Window
Chao Yin,Guohua Wen,Chao Liu,Boguang Yang,Sien Lin,Jiawei Huang,Pengchao Zhao,Siu Hong Dexter Wong,Kunyu Zhang,Xiaoyu Chen,Gang Li,Xiaohua Jiang,Jianping Huang,Kanyi Pu,Lidai Wang,Liming Bian +15 more
TL;DR: The design and synthesis of a second near-infrared (NIR-II) absorptive organic semiconducting polymer (OSP)-based nanoprobe (OSPN+) for PA imaging and tracking of stem cells is reported to facilitate a better understanding and evaluation of stem cell-based therapies.
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Self-assembled N-cadherin mimetic peptide hydrogels promote the chondrogenesis of mesenchymal stem cells through inhibition of canonical Wnt/β-catenin signaling.
TL;DR: The findings suggest that N-cadherin peptide hydrogels suppress canonical Wnt signaling in hMSCs by reducing β-catenin nuclear translocation and the associated transcriptional activity of β- catenin/LEF-1/TCF complex, thereby enhancing the chondrogenesis of h MSCs.
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Organic semiconducting polymer amphiphile for near-infrared-II light-triggered phototheranostics
Chao Yin,Xiaozhen Li,Guohua Wen,Boguang Yang,Yachao Zhang,Xiaoyu Chen,Pengchao Zhao,Shengliang Li,Rui Li,Lidai Wang,Chun-Sing Lee,Liming Bian +11 more
TL;DR: A novel NIR-II absorbing organic semiconducting polymer amphiphile (OSPA) to enhance the structural stability of OSPNs and has promising potential for fabricating multifunctional nanoplatforms to enable multimodal theranostics.
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Ultrafast self-gelling powder mediates robust wet adhesion to promote healing of gastrointestinal perforations.
Xin Peng,Xianfeng Xia,Xianfeng Xia,Xiayi Xu,Xuefeng Yang,Boguang Yang,Pengchao Zhao,Weihao Yuan,Philip Wai Yan Chiu,Liming Bian +9 more
TL;DR: In this article, a self-gelling and adhesive polyethyleneimine and polyacrylic acid (PEI/PAA) powder can absorb interfacial water to form a physically cross-linked hydrogel in situ within 2 seconds due to strong physical interactions between the polymers.