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Perry E. Bickel
Researcher at University of Texas Southwestern Medical Center
Publications - 36
Citations - 6725
Perry E. Bickel is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Lipid droplet & Perilipin. The author has an hindex of 27, co-authored 36 publications receiving 6213 citations. Previous affiliations of Perry E. Bickel include Massachusetts Institute of Technology & University of Southern Denmark.
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Journal ArticleDOI
CAP defines a second signalling pathway required for insulin-stimulated glucose transport
Baumann Christian Andrew,Baumann Christian Andrew,Vered Ribon,Vered Ribon,Makoto Kanzaki,Debbie C. Thurmond,Silvia Mora,Satoshi Shigematsu,Perry E. Bickel,Jeffrey E. Pessin,Alan R. Saltiel,Alan R. Saltiel +11 more
TL;DR: In this article, a yeast two-hybrid library using the amino-terminal region of CAP and identified the caveolar protein flotillin was used to identify a molecular mechanism underlying this subcellular redistribution.
Journal ArticleDOI
PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores
TL;DR: How the PAT proteins regulate cellular lipid metabolism both in mammals and in model organisms is discussed.
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Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins
Perry E. Bickel,Perry E. Bickel,Philipp E. Scherer,Jan E. Schnitzer,Phil Oh,Michael P. Lisanti,Harvey F. Lodish +6 more
TL;DR: Flotillin is a marker for the Triton-insoluble, buoyant membrane fraction in brain, where to date mRNA species for known caveolin gene family members have not been detected.
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Targeting adipose tissue in the treatment of obesity-associated diabetes
TL;DR: An overview of the role of adipose tissue in metabolic homeostasis is provided and emerging novel therapeutic strategies targeting adipOSE tissue are assessed, including adipokine-based strategies, promotion of white adiposa tissue beiging as well as reduction of inflammation and fibrosis.
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Minireview: Lipid Droplets in Lipogenesis and Lipolysis
TL;DR: New data suggest that proteins previously implicated in vesicle trafficking, including Rabs, soluble N-ethylmaleimide sensitive factor attachment protein receptors (SNAREs), and motor and cytoskeletal proteins, likely orchestrate the movement and fusion of lipid droplets.