Peter Pohl

TL;DR: A review of the experimental and computational advances over the past decade in understanding the role of water in the dynamics, structure, and function of proteins focuses on the combination of X-ray and neutron crystallography, NMR, terahertz spectroscopy, mass spectroscopic, thermodynamics, and computer simulations to reveal how water assist proteins in their function.

TL;DR: A review of the experimental and theoretical advances made in the last several decades in understanding the structure, dynamics, and transport of the proton and hydroxide ions in different aqueous environments, ranging from water clusters to the bulk liquid and its interfaces with hydrophobic surfaces is provided.

TL;DR: The results indicate that lipid membranes may well act as a barrier to water transport although they do not oppose a significant resistance to H2S diffusion, and the fact that cholesterol and sphingomyelin reconstitution did not turn these membranes into an H 2S barrier indicates that H1S transport through epithelial barriers, endothelial barriers and membrane rafts also occurs by simple diffusion and does not require facilitation by membrane channels.

TL;DR: Recently reported violations of the Meyer-Overton rule for small molecules, including carboxylic acids and gases, are discussed, and it is shown that Meyer and Overton continue to rule.

TL;DR: This research is the first stoichiometric study to show the selective transport of NH3 by a membrane channel and suggests that electrically silent ammonia transport may be the main function of AQP8.