P
Phalguni Gupta
Researcher at University of Pittsburgh
Publications - 149
Citations - 12047
Phalguni Gupta is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Virus & Viral load. The author has an hindex of 38, co-authored 143 publications receiving 11692 citations.
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Journal ArticleDOI
Prognosis in HIV-1 Infection Predicted by the Quantity of Virus in Plasma
John W. Mellors,Charles R. Rinaldo,Phalguni Gupta,Roseanne M. White,John Todd,Lawrence A. Kingsley +5 more
TL;DR: Plasma viral load was a better predictor of progression to AIDS and death than was the number of CD4+ T cells, and the risk of acquired immunodeficiency syndrome (AIDS) and death in study subjects was directly related to plasma viral load at study entry.
Journal ArticleDOI
Plasma Viral Load and CD4+ Lymphocytes as Prognostic Markers of HIV-1 Infection
John W. Mellors,Alvaro Muñoz,Janis V. Giorgi,Joseph B. Margolick,Charles J. Tassoni,Phalguni Gupta,Lawrence A. Kingsley,John Todd,Alfred J. Saah,Roger Detels,John P. Phair,Charles R. Rinaldo +11 more
TL;DR: This study compared the prognostic value of plasma viral load with that of clinical, serologic, and cellular markers in a large cohort of HIV-infected men and incorporated the two most predictive markers-plasma viral load and CD4+ lymphocyte count-into a regression tree that is useful for assessing the prognosis of individual patients.
Journal ArticleDOI
Consistent viral evolutionary changes associated with the progression of human immunodeficiency virus type 1 infection
Raj Shankarappa,Joseph B. Margolick,Stephen J. Gange,Allen G. Rodrigo,David Upchurch,Homayoon Farzadegan,Phalguni Gupta,Charles R. Rinaldo,Gerald H. Learn,Xi C. He,Xiao Li Huang,James I. Mullins +11 more
TL;DR: In this article, the authors studied the evolution of the C2-V5 region of the HIV-1 env gene and of T-cell subsets in nine men with a moderate or slow rate of disease progression.
Journal ArticleDOI
Quantitation of HIV-1 RNA in Plasma Predicts Outcome after Seroconversion
John W. Mellors,Lawrence A. Kingsley,Charles R. Rinaldo,John Todd,Brad S. Hoo,Robert Kokka,Phalguni Gupta +6 more
TL;DR: The objective was to compare plasma HIV-1 RNA with determinations of serum p24 antigen, neopterin, and 2-microglobulin levels and CD4+ T-cell counts as predictors of outcome in a cohort of homosexual men with documented HIV- 1 seroconversion.
Journal ArticleDOI
Kaposi's sarcoma-associated herpesvirus infection prior to onset of Kaposi's sarcoma
Patrick S. Moore,Lawrence A. Kingsley,Scott D. Holmberg,Thomas J. Spira,Phalguni Gupta,Donald R. Hoover,John Preston Parry,Lois Conley,Harold W. Jaffe,Yuan Chang +9 more
TL;DR: Findings indicate that KSHV infection is specifically associated with the subsequent development of KS in AIDS patients and Homo-/bisexual and hemophiliac AIDS patients who do not develop KS appear to have a low prevalence of infection.