P
Philip A. Poole-Wilson
Researcher at National Institutes of Health
Publications - 443
Citations - 69648
Philip A. Poole-Wilson is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Heart failure & Heart disease. The author has an hindex of 105, co-authored 443 publications receiving 66861 citations. Previous affiliations of Philip A. Poole-Wilson include Harefield Hospital & St George's Hospital.
Papers
More filters
Journal ArticleDOI
Assessment of functional capacity in chronic heart failure: time-limited exercise on a self-powered treadmill.
TL;DR: The 9-minute walking test on a self-powered treadmill is a sensitive, reproducible, safe, and inexpensive method of assessing functional capacity in patients with all grades of heart failure.
Journal ArticleDOI
Angiotensin II receptor type 1 mRNA is upregulated in atria of patients with end-stage heart failure
Raffi Kaprielian,Emmanuel Dupont,Sassan Hafizi,Philip A. Poole-Wilson,Asghar Khaghani,Magdi H. Yacoub,Magdi H. Yacoub,Nicholas J. Severs +7 more
TL;DR: The results were independent of the etiology of the heart failure and suggest that increased levels of atrial AT1R mRNA may occur in response to elevated atrial pressures in heart failure.
Journal ArticleDOI
Effect of noradrenaline and isoproterenol on lipopolysaccharide-induced tumor necrosis factor-alpha production in whole blood from patients with chronic heart failure and the role of beta-adrenergic receptors.
Stephan von Haehling,Sabine Genth-Zotz,Aidan P. Bolger,Paul R. Kalra,Michael Kemp,Ian M. Adcock,Philip A. Poole-Wilson,Rainer Dietz,Stefan D. Anker,Stefan D. Anker +9 more
TL;DR: It is demonstrated that noradrenaline and isoproterenol inhibit TNF-alpha production in patients with CHF in ex vivo whole blood in a dose-dependent fashion and the beta-blocker bisoprolol abolishes this effect.
Journal ArticleDOI
Abnormal uptake and washout of thallium-201 in patients with syndrome X and normal-appearing scans.
Giuseppe M.C. Rosano,Giuseppe M.C. Rosano,Nicholas S. Peters,Nicholas S. Peters,Juan C. Kaski,Juan C. Kaski,Sophie Mavrogeni,Sophie Mavrogeni,Peter Collins,Peter Collins,Richard Underwood,Richard Underwood,Philip A. Poole-Wilson,Philip A. Poole-Wilson +13 more
TL;DR: Analysis of uptake and washout of thallium-201 may be useful in investigating the mechanism of chest pain in patients with syndrome X and normal-appearing thallum-201 scans.
Journal ArticleDOI
Central and peripheral quadriceps fatigue in congestive heart failure.
Nicholas S Hopkinson,Mark J. Dayer,Sophie Antoine-Jonville,Elisabeth B. Swallow,Raphaël Porcher,Ali Vazir,Philip A. Poole-Wilson,Michael I. Polkey +7 more
TL;DR: The quadriceps is more susceptible to fatigue, with a similar fall in TwQ occurring in CHF patients at lower levels of exercise, and this is associated with no change in voluntary activation but a lesser degree of depression of Quadriceps motor evoked potential.