P
Philip A. Poole-Wilson
Researcher at National Institutes of Health
Publications - 443
Citations - 69648
Philip A. Poole-Wilson is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Heart failure & Heart disease. The author has an hindex of 105, co-authored 443 publications receiving 66861 citations. Previous affiliations of Philip A. Poole-Wilson include Harefield Hospital & St George's Hospital.
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Journal ArticleDOI
Modeling payback from research into the efficacy of left-ventricular assist devices as destination therapy.
Alan Girling,Guy Freeman,Jason P. Gordon,Philip A. Poole-Wilson,David A. Scott,Richard J. Lilford +5 more
TL;DR: The survival benefit that LVADs would need to generate before they could be deemed cost-effective is examined to provide insight into the likelihood that this benefit will be achieved and the value of discovering the actual size of this benefit by means of a Bayesian value of information analysis.
Journal ArticleDOI
Lower patients' cholesterol now.
TL;DR: The first principle of the lipid hypothesis is that raised plasma cholesterol concentrations are associated with a high incidence of atherosclerosis and an increased risk of coronary heart disease, and the second principle—that both this risk and total mortality can be reduced by lowering cholesterol concentrations—remains controversial.
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Effect of carvedilol and metoprolol on the mode of death in patients with heart failure.
Willem J. Remme,John G.F. Cleland,Leif Rw Erhardt,Phillip Spark,Christian Torp-Pedersen,Marco Metra,Michel Komajda,Christine Moullet,Mary Ann Lukas,Philip A. Poole-Wilson,Andrea Di Lenarda,Karl Swedberg +11 more
TL;DR: In the COMET study, carvedilol improved survival compared to metoprolol tartrate in 3029 patients with NYHA II–IV heart failure and EF <35%, followed for an average of 58months.
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Impaired baroreflex sensitivity and sympathovagal balance in syndrome X.
Stamatis Adamopoulos,Giuseppe M.C. Rosano,Piotr Ponikowski,Elena Cerquetani,Massimo F. Piepoli,Flevari Panagiota,Peter Collins,Philip A. Poole-Wilson,Dimitrios Th. Kremastinos,Andrew J.S. Coats +9 more
TL;DR: Patients with syndrome X have an altered autonomic control of the cardiovascular system characterized by impaired baroreceptor sensitivity and reduced heart rate variability, which may be of pathophysiologic importance in syndrome X.
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Deficiencies in circulating testosterone and dehydroepiandrosterone sulphate, and depression in men with systolic chronic heart failure.
Ewa A. Jankowska,Ewa A. Jankowska,Anna Drohomirecka,Beata Ponikowska,Agnieszka Witkowska,Monika Lopuszanska,Alicja Szklarska,Ludmila Borodulin-Nadzieja,Waldemar Banasiak,Philip A. Poole-Wilson,Piotr Ponikowski +10 more
TL;DR: Elderly men with androgen deficiencies are prone to develop late‐onset depression and their combined impact on outcome in men with chronic heart failure (CHF) is investigated.