P
Philip A. Poole-Wilson
Researcher at National Institutes of Health
Publications - 443
Citations - 69648
Philip A. Poole-Wilson is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Heart failure & Heart disease. The author has an hindex of 105, co-authored 443 publications receiving 66861 citations. Previous affiliations of Philip A. Poole-Wilson include Harefield Hospital & St George's Hospital.
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Journal ArticleDOI
Ursodeoxycholic acid in patients with chronic heart failure: a double-blind, randomized, placebo-controlled, crossover trial.
Stephan von Haehling,Joerg C. Schefold,Ewa A. Jankowska,Jochen Springer,Jochen Springer,Ali Vazir,Paul R. Kalra,Anja Sandek,Günter Fauler,Tatjana Stojakovic,Michael Trauner,Piotr Ponikowski,Hans-Dieter Volk,Wolfram Doehner,Andrew J.S. Coats,Philip A. Poole-Wilson,Stefan D. Anker +16 more
TL;DR: UDCA improves peripheral blood flow and is associated with improved markers of liver function, and is well tolerated in patients with CHF.
Journal ArticleDOI
Cellular mechanisms of contractile dysfunction in human heart failure.
TL;DR: The increasing use of cardiac transplantation has provided access to fresh myocardial tissue from severely failing human hearts and this has generated a large volume of experimental data, resulting in a classification of the cellular abnormalities encountered in the failing human heart.
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Treatment of chronic heart failure: a review of recent drug trials.
TL;DR: Enthoven identifies national uniformity and political haste as stultifying the aims of the management changes and believes that the introduction of an "internal market model" for the NHS could promote better management and loosen the gridlock in the NHS.
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Circulatory support for long-term treatment of heart failure: experience with an intraventricular continuous flow pump.
Stephen Westaby,Adrian P. Banning,Satoshi Saito,David Pigott,Xu Yu Jin,Pedro A Catarino,Desiree Robson,Narain Moorjani,Attila Kardos,Philip A. Poole-Wilson,Robert Jarvik,O.H. Frazier +11 more
TL;DR: The Jarvik 2000 is a true assist (rather than replacement) device that functions synergistically with the native left ventricle and provides excellent quality of life and this blood pump may provide a mechanical solution for end-stage heart failure in the community.
Journal ArticleDOI
A Comparison of the Effects of Carvedilol and Metoprolol on Well-Being, Morbidity, and Mortality (the “Patient Journey”) in Patients With Heart Failure: A Report From the Carvedilol Or Metoprolol European Trial (COMET)
John G.F. Cleland,Andrew Charlesworth,Jacobus Lubsen,Karl Swedberg,Willem J. Remme,Leif Rw Erhardt,Andrea Di Lenarda,Michel Komajda,Marco Metra,Christian Torp-Pedersen,Philip A. Poole-Wilson,Comet investigators +11 more
TL;DR: Compared with metoprolol, carvedilol was associated with fewer days lost to death, with no increase in days lost due to impaired well-being or days in hospital, and the "patient journey" score improved.