P
Philipp Kukura
Researcher at University of Oxford
Publications - 159
Citations - 9125
Philipp Kukura is an academic researcher from University of Oxford. The author has contributed to research in topics: Femtosecond & Raman spectroscopy. The author has an hindex of 43, co-authored 143 publications receiving 7445 citations. Previous affiliations of Philipp Kukura include ETH Zurich & University of Duisburg-Essen.
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Journal ArticleDOI
Conical intersection dynamics of the primary photoisomerization event in vision
Dario Polli,Piero Altoè,Oliver Weingart,Katelyn M. Spillane,Cristian Manzoni,Daniele Brida,Gaia Tomasello,G. Orlandi,Philipp Kukura,Richard A. Mathies,Marco Garavelli,Giulio Cerullo +11 more
TL;DR: Ultrafast optical spectroscopy with sub-20-fs time resolution and spectral coverage from the visible to the near-infrared allows us to follow the dynamics leading to the conical intersection in rhodopsin isomerization and finds excellent agreement between the experimental observations and molecular dynamics calculations that involve a true electronic state crossing.
Journal ArticleDOI
Structural observation of the primary isomerization in vision with femtosecond-stimulated Raman.
TL;DR: The spectral evolution of the vibrational features from 200 femtoseconds to 1 picosecond after photon absorption reveals the temporal sequencing of the geometric changes in the retinal backbone that activate this receptor.
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Femtosecond stimulated Raman spectroscopy.
TL;DR: Femtosecond stimulated Raman spectroscopy (FSRS) is a new ultrafast spectroscopic technique that provides vibrational structural information with high temporal (50-fs) and spectral (10-cm(1)) resolution as mentioned in this paper.
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Quantitative mass imaging of single biological macromolecules
Gavin Young,Nikolas Hundt,Daniel Cole,Adam Fineberg,Joanna Andrecka,Andrew Tyler,Anna Olerinyova,A Ansari,Erik G. Marklund,Miranda P. Collier,Shane A. Chandler,Olga Tkachenko,Joel D. Allen,Max Crispin,Neil Billington,Yasuharu Takagi,James R. Sellers,Cédric Eichmann,Philipp Selenko,Lukas Frey,Roland Riek,Roland Riek,Martin R. Galpin,Weston B. Struwe,Justin L. P. Benesch,Philipp Kukura +25 more
TL;DR: Interferometric scattering mass spectrometry allows spatiotemporally resolved measurement of a broad range of biomolecular interactions, one molecule at a time, to characterize the molecular dynamics of processes as diverse as glycoprotein cross-linking, amyloidogenic protein aggregation, and actin polymerization.
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High-speed nanoscopic tracking of the position and orientation of a single virus.
TL;DR: A colocalization methodology that combines scattering interferometry and single-molecule fluorescence microscopy to visualize both position and orientation of single quantum dot–labeled Simian virus 40 (SV40) particles suggests recurrent swap of receptors and viral pentamers as well as receptor aggregation in nanodomains.