scispace - formally typeset
P

Pierluigi Baron

Researcher at University of Milan

Publications -  60
Citations -  4424

Pierluigi Baron is an academic researcher from University of Milan. The author has contributed to research in topics: Schwann cell & Myelin. The author has an hindex of 31, co-authored 60 publications receiving 4155 citations. Previous affiliations of Pierluigi Baron include Thomas Jefferson University & Children's Hospital of Philadelphia.

Papers
More filters
Journal ArticleDOI

Activation of microglial cells by beta-amyloid protein and interferon-gamma

TL;DR: In this article, a synergistic effect between A beta and interferon-gamma was found to trigger the production of reactive nitrogen intermediates and tumour-necrosis factor-alpha (TNF-alpha) from microglia.
Journal ArticleDOI

Glial activation in Alzheimer’s disease: the role of Aβ and its associated proteins

TL;DR: Unraveling the mechanisms by which Abeta and expression of its associated molecules represent important trigger factors in glial activation leading to an inflammatory reaction in the brain may provide significant insight into the pathophysiology of AD and may lead to the identification of new strategies for AD treatment.
Journal ArticleDOI

Sulfatides trigger increase of cytosolic free calcium and enhanced expression of tumor necrosis factor-alpha and interleukin-8 mRNA in human neutrophils. Evidence for a role of L-selectin as a signaling molecule.

TL;DR: It is found that sulfatides trigger the increase of cytosolic free calcium in neutrophils and that this effect was strictly dependent on sulfation of the galactose ring, as non-sulfated galactocerebrosides were not stimulatory.
Journal ArticleDOI

Oxidative imbalance in patients with mild cognitive impairment and Alzheimer's disease

TL;DR: A pattern characterized by increased tHcy levels and decreased TAC is present in AD as well as MCI patients, and ROS levels appear to be correlated with age rather than with a specific dementing disorder, thus leading to the hypothesis that oxidative imbalance observed in AD could be due to a decreases TAC.
Journal ArticleDOI

Acute Cerebrovascular Disease in the Young The Stroke in Young Fabry Patients Study

Arndt Rolfs, +313 more
- 01 Feb 2013 - 
TL;DR: Silent infarcts, white matter intensities, and classical risk factors were highly prevalent, emphasizing the need for new early preventive strategies.