Carsten Hobohm

TL;DR: Among patients with OAC-associated ICH, reversal of anticoagulation reversal and blood pressure (BP) with hematoma enlargement and resumption of OAC therapy was associated with lower risk of ischemic events, and these findings require replication and assessment in prospective studies.

TL;DR: Hemicraniectomy increased survival without severe disability among patients 61 years of age or older with a malignant middle-cerebral-artery infarction and the majority of survivors required assistance with most bodily needs.

TL;DR: Silent infarcts, white matter intensities, and classical risk factors were highly prevalent, emphasizing the need for new early preventive strategies.

TL;DR: In patients who have had a stroke with unknown time of onset with a DWI-FLAIR or perfusion mismatch, intravenous alteplase resulted in better functional outcome at 90 days than placebo or standard care despite an increased risk of symptomatic intracranial haemorrhage.

TL;DR: It is concluded that complementary to the known upregulation of matrix components in the glial scar, deficits in the expression of the neuron‐associated extracellular matrix develop in the periinfarct and remote regions and may contribute to the long‐lasting functional impairments after stroke.