Pierre Celsis

TL;DR: Using a normalized thickness index-based criterion may help with early diagnosis of Alzheimer's disease at the individual level, especially for highly educated subjects, up to 24 months before clinical criteria for Alzheimer's Disease diagnosis are met.

TL;DR: Parkinson-associated physiopathological modifications were characterized in six subcortical structures by simultaneously measuring quantitative magnetic resonance parameters sensitive to complementary tissue characteristics, demonstrating that multimodal magnetic resonance imaging of sub cortical grey matter structures is useful for the evaluation of Parkinson's disease and, possibly, of other subcortsical pathologies.

TL;DR: The analysis of the decreases and increases in the BOLD signal across the STD, DEV, and rest conditions suggests that the left posterior superior temporal gyrus is implicated in the preattentive change detection of acoustic changes in speech as well as nonspeech stimuli, whereas the left supramarginal g Cyrus is more specifically engaged in the detection of changes in phonological units.

TL;DR: The hypothesis that a functional cortical motor area deafferentation is involved in the pathophysiological makeup of akinesia and that this abnormality is reversed by dopaminergic drugs is supported.

TL;DR: MRSI and CE abnormalities are now integrated for glioblastoma SIB-IMRT, concomitant with temozolomide, in an ongoing multi-institutional phase-III clinical trial.