Umberto Sabatini

TL;DR: Parkinson-associated physiopathological modifications were characterized in six subcortical structures by simultaneously measuring quantitative magnetic resonance parameters sensitive to complementary tissue characteristics, demonstrating that multimodal magnetic resonance imaging of sub cortical grey matter structures is useful for the evaluation of Parkinson's disease and, possibly, of other subcortsical pathologies.

TL;DR: The present investigation aimed at exploring the anatomical substrate of both extrapersonal and personal neglect by using different advanced methodological approaches to lesion-function correlation, which suggested a segregation of personal and extrapERSONal spatial awareness in humans.

TL;DR: The hypothesis that a functional cortical motor area deafferentation is involved in the pathophysiological makeup of akinesia and that this abnormality is reversed by dopaminergic drugs is supported.

TL;DR: The results suggest that parkinsonian patients off medication may try to compensate for their basal ganglia-cortical loop's dysfunction using other motor pathways involving cerebellar relays.

TL;DR: The statistical analyses highlighted characteristic patterns of variation for the measurements in the various structures evaluated in this study, which contribute in establishing a baseline for comparison with pathological changes in the basal ganglia and thalamus.