P
Pietro De Camilli
Researcher at Yale University
Publications - 338
Citations - 51433
Pietro De Camilli is an academic researcher from Yale University. The author has contributed to research in topics: Endocytic cycle & Dynamin. The author has an hindex of 120, co-authored 318 publications receiving 47033 citations. Previous affiliations of Pietro De Camilli include Osaka University & Harvard University.
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Journal ArticleDOI
A Novel Pathway for Presynaptic Mitogen-Activated Kinase Activation via AMPA Receptors
Ursula Schenk,Elisabetta Menna,Taeyong Kim,Maria Passafaro,Sunghoe Chang,Pietro De Camilli,Michela Matteoli +6 more
TL;DR: It is shown that stimulation of presynaptic AMPA receptors induces activation of mitogen-activated protein kinase (MAPK) through a nonreceptor tyrosine kinase-dependent and Na+/Ca2+-independent mechanism and this pathway is activated predominantly in axonal growth cones compared with the somatodendritic compartment.
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Expression of amphiphysin I, an autoantigen of paraneoplastic neurological syndromes, in breast cancer.
Scott R. Floyd,Margaret H. Butler,Ottavio Cremona,Carol David,Zachary Freyberg,Xiaomei Zhang,Michele Solimena,Akira Tokunaga,Hideki Ishizu,Kimiko Tsutsui,Pietro De Camilli +10 more
TL;DR: The enhanced expression of amphiphysin I in some forms of cancer supports the hypothesis that amphiphYSin family members may play a role in the biology of cancer cells.
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Yersinia Entry into Host Cells Requires Rab5-Dependent Dephosphorylation of PI(4,5)P2 and Membrane Scission
Helen Sarantis,Daniel M. Balkin,Pietro De Camilli,Ralph R. Isberg,John H. Brumell,Sergio Grinstein +5 more
TL;DR: Yersinia invasion involves a multistep process in which the bacteria form a protective prevacuole and then recruit host factors to induce membrane fission, allowing the bacteria to invade the cell.
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All known patient mutations in the ASH-RhoGAP domains of OCRL affect targeting and APPL1 binding
Heather J. McCrea,Summer Paradise,Livia Tomasini,Maria Addis,Maria Antonietta Melis,Maria Antonietta De Matteis,Pietro De Camilli +6 more
TL;DR: This work provides new evidence showing that among the interactions which target OCRL to membranes of the endocytic pathway, binding to APPL1 is the only one abolished by all known disease-causing missense mutations in the ASH-RhoGAP domains of the protein.
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Regulated secretory pathways of neurons and their relation to the regulated secretory pathway of endocrine cells.
TL;DR: Findings have indicated that, even though some features may be common to regulated exocytosis of all secretory organelles of all cell types:.9 neuronal secretion via SSVs might be characterized by some special type of regulation.