P
Pietro Rizza
Researcher at University of Calabria
Publications - 31
Citations - 1848
Pietro Rizza is an academic researcher from University of Calabria. The author has contributed to research in topics: Estrogen receptor alpha & Breast cancer. The author has an hindex of 21, co-authored 30 publications receiving 1642 citations.
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Journal ArticleDOI
Leptin Enhances, via AP-1, Expression of Aromatase in the MCF-7 Cell Line *
Stefania Catalano,Stefania Marsico,Cinzia Giordano,Loredana Mauro,Pietro Rizza,Maria Luisa Panno,Sebastiano Andò +6 more
TL;DR: The possible link that exists between leptin and breast cancer is examined, focusing on the direct effect of leptin on aromatase activity, which may enhance estrogen production and induce tumor cell growth stimulation.
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Leptin Induces, via ERK1/ERK2 Signal, Functional Activation of Estrogen Receptor α in MCF-7 Cells
Stefania Catalano,Loredana Mauro,Stefania Marsico,Cinzia Giordano,Pietro Rizza,Vittoria Rago,Daniela Montanaro,Marcello Maggiolini,Maria Luisa Panno,Sebastiano Andò +9 more
TL;DR: It is demonstrated that leptin induces aromatase activity in MCF-7 cells evidencing its important role in enhancing in situ estradiol production and promoting estrogen-dependent breast cancer progression.
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Oleuropein and hydroxytyrosol inhibit MCF‐7 breast cancer cell proliferation interfering with ERK1/2 activation
Rosa Sirianni,Adele Chimento,Arianna De Luca,Ivan Casaburi,Pietro Rizza,Arianna Onofrio,Domenico Iacopetta,Francesco Puoci,Sebastiano Andò,Marcello Maggiolini,Vincenzo Pezzi +10 more
TL;DR: It is demonstrated that HT and OL can have a chemo-preventive role in breast cancer cell proliferation through the inhibition of estrogen-dependent rapid signals involved in uncontrolled tumor cell growth.
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Estrogen receptor beta as a novel target of androgen receptor action in breast cancer cell lines
Pietro Rizza,Ines Barone,D Zito,Francesca Giordano,Marilena Lanzino,Francesca De Amicis,Loredana Mauro,Diego Sisci,Stefania Catalano,Karin Dahlman Wright,Jan-Åke Gustafsson,Sebastiano Andò +11 more
TL;DR: It is demonstrated that mibolerone, a synthetic androgen ligand, up-regulates ER-beta mRNA and protein levels in ER-positive breast cancer cells and provides evidence for a novel mechanism by which activated AR, through an up-regulation of ER- beta gene expression, inhibits breast cancer cell growth.
Journal ArticleDOI
Evidence that leptin through STAT and CREB signaling enhances cyclin D1 expression and promotes human endometrial cancer proliferation.
Stefania Catalano,Cinzia Giordano,Pietro Rizza,Guowei Gu,Ines Barone,Daniela Bonofiglio,Francesca Giordano,Rocco Malivindi,Donatella Gaccione,Marilena Lanzino,Francesca De Amicis,Sebastiano Andò +11 more
TL;DR: Results support the hypothesis that STAT3 and CREB play an important role in leptin signaling pathway that leads to the proliferation of Ishikawa cells, thus establishing a direct association between obesity and endometrial tumorogenesis.