P
Pietro Tiraboschi
Researcher at Carlo Besta Neurological Institute
Publications - 100
Citations - 6786
Pietro Tiraboschi is an academic researcher from Carlo Besta Neurological Institute. The author has contributed to research in topics: Dementia & Medicine. The author has an hindex of 26, co-authored 63 publications receiving 5087 citations. Previous affiliations of Pietro Tiraboschi include University of Chieti-Pescara & University of Cambridge.
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Journal ArticleDOI
Longitudinal Cognitive Changes in Genetic Frontotemporal Dementia Within the GENFI Cohort
Jackie M. Poos,Amy Macdougall,Esther van den Berg,Lize C. Jiskoot,Janne M. Papma,Emma L. van der Ende,Harro Seelaar,Lucy L. Russell,Georgia Peakman,Rhian S Convery,Yolande A.L. Pijnenburg,Fermin Moreno,Raquel Sánchez-Valle,S. Borroni,Robert Laforce,Marie-Claire DorÃ,Mario Masellis,Maria Carmela Tartaglia,Caroline Graff,Daniela Galimberti,James B. Rowe,Elizabeth Finger,Matthis Synofzik,Rik Vandenberghe,Alexandre de Mendonça,Pietro Tiraboschi,Isabel Santana,Simon Ducharme,Christopher C Butler,Alexander Gerhard,Johannes Levin,Adrian Danek,Markus Otto,Isabelle Le Ber,Florence Pasquier,John C. van Swieten,Jonathan D. Rohrer +36 more
TL;DR: Cognitive decline in the asymptomatic and prodromal stage of genetic FTD is confirmed and confirms the value of neuropsychological assessment in tracking clinical onset and progression and could inform clinical trials in selecting sensitive end points for measuring treatment effects.
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Neuropsychiatric symptoms in genetic frontotemporal dementia: developing a new module for Clinical Rating Scales
Kiran Samra,Amy Macdougall,Georgia Peakman,Arabella Bouzigues,Martina Bocchetta,David M. Cash,Caroline V. Greaves,Rhian S Convery,John C. van Swieten,Lize C. Jiskoot,Harro Seelaar,Fermin Moreno,Raquel Sánchez-Valle,Robert Laforce,Caroline Graff,Mario Masellis,Maria Carmela Tartaglia,James B. Rowe,S. Borroni,Elizabeth Finger,Matthis Synofzik,Daniela Galimberti,Rik Vandenberghe,Alexandre de Mendonça,Christopher C Butler,Alexander Gerhard,Simon Ducharme,Isabelle Le Ber,Pietro Tiraboschi,Isabel Santana,Florence Pasquier,Johannes Levin,Markus Otto,Sandro Sorbi,Jonathan D. Rohrer,Lucy L. Russell +35 more
TL;DR: In this paper , the authors proposed a new neuropsychiatric module that could be used as an addition to the Clinical Dementia Rating (CDR) plus National Alzheimer's Coordinating Center Behaviour and Language Domains (NACC FTLD) rating scale.
Journal ArticleDOI
Cerebrospinal Fluid EV Concentration and Size Are Altered in Alzheimer’s Disease and Dementia with Lewy Bodies
Antonio Longobardi,Roland Nicsanu,Sonia Bellini,Rosanna Squitti,Marcella Catania,Pietro Tiraboschi,Claudia Saraceno,Clarissa Ferrari,Roberta Zanardini,Giuliano Binetti,Giuseppe Di Fede,Luisa Benussi,Roberta Ghidoni +12 more
TL;DR: A common involvement of the endosomal pathway in neurodegenerative dementias is suggested, giving important insight into the molecular mechanisms underlying these pathologies.
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CSF glial markers are elevated in a subset of patients with genetic frontotemporal dementia
Ione O.C. Woollacott,Imogen Swift,Aitana Sogorb-Esteve,Carolin Heller,Kathryn E. Knowles,Arabella Bouzigues,Lucy L. Russell,Georgia Peakman,Caroline V. Greaves,Rhian S Convery,Amanda Heslegrave,James B. Rowe,S. Borroni,Daniela Galimberti,Pietro Tiraboschi,Mario Masellis,Maria Carmela Tartaglia,Elizabeth Finger,John C. van Swieten,Harro Seelaar,Lize C. Jiskoot,Sandro Sorbi,Christopher C Butler,Caroline Graff,Alexander Gerhard,Robert Laforce,Raquel Sánchez-Valle,Alexandre de Mendonça,Fermin Moreno,Matthis Synofzik,Rik Vandenberghe,Simon Ducharme,Isabelle Le Ber,Johannes Levin,Markus Otto,Florence Pasquier,Isabel Santana,Henrik Zetterberg,Jonathan D. Rohrer +38 more
TL;DR: In this paper , the activation of microglia, a process that can be measured in life through assaying different glia-derived biomarkers in cerebrospinal fluid, was shown to be an important pathophysiological disease mechanism in frontotemporal dementia.
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PMCA-Based Detection of Prions in the Olfactory Mucosa of Patients With Sporadic Creutzfeldt–Jakob Disease
Federico Angelo Cazzaniga,Edoardo Bistaffa,Chiara De Luca,Sara Maria Portaleone,Marcella Catania,Veronica Redaelli,Irene Tramacere,Giuseppe Bufano,Martina Rossi,Paola Caroppo,Anna Rita Giovagnoli,Pietro Tiraboschi,Giuseppe Di Fede,Roberto Eleopra,Grazia Devigili,Antonio E. Elia,Roberto Cilia,Michele Fiorini,Matilde Bongianni,Giulia Salzano,Luigi Celauro,Federico Giuseppe Quarta,Angela Mammana,Giuseppe Legname,Fabrizio Tagliavini,Piero Parchi,Gianluigi Zanusso,Giorgio Giaccone,Fabio Moda +28 more
TL;DR: Although the optimized PMCA did not consent to recognize sCJD subtypes from the analysis of OM collected from living patients, it enabled us to estimate for the first time the amount of prions accumulating in this biological tissue.