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Simon Ducharme
Researcher at McGill University Health Centre
Publications - 140
Citations - 3254
Simon Ducharme is an academic researcher from McGill University Health Centre. The author has contributed to research in topics: Frontotemporal dementia & Medicine. The author has an hindex of 24, co-authored 93 publications receiving 2054 citations. Previous affiliations of Simon Ducharme include Montreal General Hospital & Douglas Mental Health University Institute.
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Journal ArticleDOI
Trajectories of cortical thickness maturation in normal brain development--The importance of quality control procedures.
Simon Ducharme,Simon Ducharme,Matthew D. Albaugh,Tuong-Vi Nguyen,James J. Hudziak,José María Mateos-Pérez,Aurélie Labbe,Alan C. Evans,Sherif Karama,Sherif Karama +9 more
TL;DR: It is suggested that CTh follows a simple linear decline in most cortical areas by age 5, and all areas byage 8, which further supports the crucial importance of implementing post-processing QC in CTh studies of development, aging, and neuropsychiatric disorders.
Journal ArticleDOI
Anxious/Depressed Symptoms are Linked to Right Ventromedial Prefrontal Cortical Thickness Maturation in Healthy Children and Young Adults
Simon Ducharme,Matthew D. Albaugh,James J. Hudziak,Kelly N. Botteron,Tuong-Vi Nguyen,Catherine Truong,Alan C. Evans,Sherif Karama +7 more
TL;DR: The dynamic impact of age on relations between vmPFC and negative affect in the developing brain is demonstrated and potential neurobiological mechanisms underlying this maturation pattern are proposed.
Journal ArticleDOI
Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study.
Katrina M. Moore,Jennifer M. Nicholas,Murray Grossman,Corey T. McMillan,David J. Irwin,Lauren Massimo,Vivianna M. Van Deerlin,Jason D. Warren,Nick C. Fox,Martin N. Rossor,Simon Mead,Martina Bocchetta,Bradley F. Boeve,David S. Knopman,Neill Graff-Radford,Leah K. Forsberg,Rosa Rademakers,Zbigniew K. Wszolek,John C. van Swieten,Lize C. Jiskoot,Lieke H.H. Meeter,Elise G.P. Dopper,Janne M. Papma,Julie S. Snowden,Jennifer A. Saxon,Matthew Jones,Stuart Pickering-Brown,Isabelle Le Ber,Agnès Camuzat,Alexis Brice,Paola Caroppo,Roberta Ghidoni,Michela Pievani,Luisa Benussi,Giuliano Binetti,Bradford C. Dickerson,Diane Lucente,Samantha Krivensky,Caroline Graff,Linn Öijerstedt,Marie Fallström,Håkan Thonberg,Nupur Ghoshal,John C. Morris,Barbara Borroni,Alberto Benussi,Alessandro Padovani,Daniela Galimberti,Elio Scarpini,Giorgio G. Fumagalli,Giorgio G. Fumagalli,Ian R. Mackenzie,Ging-Yuek Robin Hsiung,Pheth Sengdy,Adam L. Boxer,Howie Rosen,Joanne Taylor,Matthis Synofzik,Matthis Synofzik,Carlo Wilke,Carlo Wilke,Patricia Sulzer,Patricia Sulzer,John R. Hodges,Glenda M. Halliday,John B.J. Kwok,Raquel Sánchez-Valle,Albert Lladó,Sergi Borrego-Écija,Isabel Santana,Maria Rosário Almeida,Miguel Tábuas-Pereira,Fermin Moreno,Myriam Barandiaran,Begoña Indakoetxea,Johannes Levin,Johannes Levin,Adrian Danek,James B. Rowe,Thomas E. Cope,Markus Otto,Sarah Anderl-Straub,Alexandre de Mendonça,Carolina Maruta,Mario Masellis,Sandra E. Black,Philippe Couratier,Géraldine Lautrette,Edward D. Huey,Sandro Sorbi,Benedetta Nacmias,Robert Laforce,Marie Pier L. Tremblay,Rik Vandenberghe,Philip Van Damme,Philip Van Damme,Emily Rogalski,Sandra Weintraub,Alexander Gerhard,Alexander Gerhard,Chiadi U. Onyike,Simon Ducharme,Sokratis G. Papageorgiou,Adeline Su Lyn Ng,Amy Brodtmann,Elizabeth Finger,Rita Guerreiro,Jose Bras,Jonathan D. Rohrer,Carolin Heller,Rhian S Convery,Ione O.C. Woollacott,Rachelle Shafei,Jonathan Graff-Radford,David T.W. Jones,Christina Dheel,Rodolfo Savica,Maria I. Lapid,Matt Baker,Julie A. Fields,Ralitza H. Gavrilova,Kimiko Domoto-Reilly,Jackie M. Poos,Emma L. van der Ende,Jessica L. Panman,Laura Donker Kaat,Harro Seelaar,Anna Richardson,Giovanni B. Frisoni,Anna Mega,Silvia Fostinelli,Huei Hsin Chiang,Antonella Alberici,Andrea Arighi,Chiara Fenoglio,Hilary W. Heuer,Bruce L. Miller,Anna Karydas,Jamie Fong,Maria João Leitão,Beatriz Santiago,Diana Duro,Carlos Ferreira,Alazne Gabilondo,Maria de Arriba,Mikel Tainta,Miren Zulaica,Catarina S. Ferreira,Elisa Semler,Albert C. Ludolph,Bernhard Landwehrmeyer,Alexander E Volk,Gabriel Miltenberger,Ana Verdelho,Sónia Afonso,Maria Carmela Tartaglia,Morris Freedman,Ekaterina Rogaeva,Camilla Ferrari,Irene Piaceri,Valentina Bessi,Gemma Lombardi,Frédéric St-Onge,Marie Claire Doré,Rose Bruffaerts,Mathieu Vandenbulcke,Jan Van den Stock,M.-Marsel Mesulam,Eileen H. Bigio,Christos Koros,John Papatriantafyllou,Christos Kroupis,Leonidas Stefanis,Christien Shoesmith,Erik Robertson,Giovanni Coppola,Eliana Marisa Ramos,Daniel H. Geschwind +177 more
TL;DR: An international study of age at symptom onset, age at death, and disease duration in individuals with mutations in GRN, MAPT, and C9orf72 to investigate the extent to which variability in age at onset and at death could be accounted for by family membership and the specific mutation carried.
Journal ArticleDOI
Testosterone-Related Cortical Maturation Across Childhood and Adolescence
Tuong-Vi Nguyen,James T. McCracken,Simon Ducharme,Kelly N. Botteron,Megan Mahabir,Wendy Johnson,Mimi Israel,Alan C. Evans,Sherif Karama,Sherif Karama +9 more
TL;DR: Findings show the association between testosterone and CTh to be complex, highly dynamic, and to vary, depending on sex and age; they also suggest sex-related hemispheric lateralization effects of testosterone in humans.
Journal ArticleDOI
Cigarette smoking and thinning of the brain’s cortex
Sherif Karama,Simon Ducharme,Janie Corley,Francois Chouinard-Decorte,John M. Starr,Joanna M. Wardlaw,Mark E. Bastin,Ian J. Deary +7 more
TL;DR: The data suggest that smoking is associated with diffuse accelerated cortical thinning, a biomarker of cognitive decline in adults, and partial recovery appears possible, although partial recovery seems possible, it can be a long process.