E
Elizabeth Finger
Researcher at University of Western Ontario
Publications - 206
Citations - 9152
Elizabeth Finger is an academic researcher from University of Western Ontario. The author has contributed to research in topics: Frontotemporal dementia & Medicine. The author has an hindex of 45, co-authored 139 publications receiving 7081 citations. Previous affiliations of Elizabeth Finger include St. Joseph Hospital & University of Lisbon.
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Journal ArticleDOI
Reduced Amygdala Response to Fearful Expressions in Children and Adolescents With Callous-Unemotional Traits and Disruptive Behavior Disorders
Abigail A. Marsh,Elizabeth Finger,Derek G.V. Mitchell,Marguerite E. Reid,Courtney Sims,David S. Kosson,Kenneth E. Towbin,Ellen Leibenluft,Daniel S. Pine,R.J.R. Blair +9 more
TL;DR: These findings support the contention that callous and unemotional personality traits are associated with reduced amygdala response to distress-based social cues.
Journal ArticleDOI
TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics
Ian R. A. Mackenzie,Alexandra M. Nicholson,Mohona Sarkar,James Messing,Maria D. Purice,Cyril Pottier,Kavya Annu,Matt Baker,Ralph B. Perkerson,Aishe Kurti,Billie J. Matchett,Tanja Mittag,Jamshid Temirov,Ging-Yuek Robin Hsiung,Charles Krieger,Charles Krieger,Melissa E. Murray,Masato Kato,John D. Fryer,Leonard Petrucelli,Lorne Zinman,Sandra Weintraub,M.-Marsel Mesulam,Julia Keith,Sasha Zivkovic,Veronica Hirsch-Reinshagen,Raymond P. Roos,Stephan Züchner,Neill R. Graff-Radford,Ronald C. Petersen,Richard J. Caselli,Zbigniew K. Wszolek,Elizabeth Finger,Carol F. Lippa,Carol F. Lippa,David Lacomis,Heather Stewart,Dennis W. Dickson,Hong Joo Kim,Ekaterina Rogaeva,Eileen H. Bigio,Kevin B. Boylan,J. Paul Taylor,Rosa Rademakers +43 more
TL;DR: The identification of TIA1 mutations in ALS/FTD reinforces the importance of RNA metabolism and SG dynamics in ALS-FTD pathogenesis.
Journal ArticleDOI
Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis
Jonathan D. Rohrer,Jennifer M. Nicholas,Jennifer M. Nicholas,David M. Cash,John C. van Swieten,Elise G.P. Dopper,Lize C. Jiskoot,Rick van Minkelen,Serge A.R.B. Rombouts,M. Jorge Cardoso,Shona Clegg,Miklos Espak,Simon Mead,David L. Thomas,Enrico De Vita,Mario Masellis,Sandra E. Black,Morris Freedman,Ron Keren,Bradley J. MacIntosh,Ekaterina Rogaeva,David F. Tang-Wai,Maria Carmela Tartaglia,Robert Laforce,Fabrizio Tagliavini,Pietro Tiraboschi,Veronica Redaelli,Sara Prioni,Marina Grisoli,Barbara Borroni,Alessandro Padovani,Daniela Galimberti,Elio Scarpini,Andrea Arighi,Giorgio G. Fumagalli,James B. Rowe,Ian Coyle-Gilchrist,Caroline Graff,Caroline Graff,Marie Fallström,Vesna Jelic,Vesna Jelic,Anne Kinhult Ståhlbom,Anne Kinhult Ståhlbom,Christin Andersson,Christin Andersson,Håkan Thonberg,Håkan Thonberg,Lena Lilius,Giovanni B. Frisoni,Giuliano Binetti,Michela Pievani,Martina Bocchetta,Luisa Benussi,Roberta Ghidoni,Elizabeth Finger,Sandro Sorbi,Benedetta Nacmias,Gemma Lombardi,Cristina Polito,Jason D. Warren,Sebastien Ourselin,Nick C. Fox,Martin N. Rossor +63 more
TL;DR: Structural imaging and cognitive changes can be identified 5-10 years before expected onset of symptoms in asymptomatic adults at risk of genetic frontotemporal dementia, which could help to define biomarkers that can stage presymPTomatic disease and track disease progression.
Journal ArticleDOI
Eosinophil recruitment to the lung in a murine model of allergic inflammation. The role of T cells, chemokines, and adhesion receptors.
Jose Angel Gonzalo,Clare M. Lloyd,Leonor Kremer,Elizabeth Finger,Carlos Martínez-A,M. H. Siegelman,Myron I. Cybulsky,Jose-Carlos Gutierrez-Ramos +7 more
TL;DR: Blockade of eotaxin with specific antibodies in vivo reduced the accumulation of eosinophils in the lung in response to OVA by half, and mice genetically deficient for VCAM-1 and intercellular adhesion molecule-1 failed to develop pulmonary eOSinophilia.
Journal ArticleDOI
Abnormal ventromedial prefrontal cortex function in children with psychopathic traits during reversal learning.
Elizabeth Finger,Abigail A. Marsh,Derek G.V. Mitchell,Marguerite E. Reid,Courtney Sims,Salima Budhani,David S. Kosson,Gang Chen,Kenneth E. Towbin,Ellen Leibenluft,Daniel S. Pine,James R. Blair +11 more
TL;DR: This study provides the first evidence of abnormal ventromedial prefrontal cortex responsiveness in children with psychopathic traits and demonstrates this dysfunction was not attributable to comorbid attention-deficit/hyperactivity disorder.