P
Prabhav Kalaghatgi
Researcher at Max Planck Society
Publications - 17
Citations - 317
Prabhav Kalaghatgi is an academic researcher from Max Planck Society. The author has contributed to research in topics: Phylogenetic tree & Minimum spanning tree. The author has an hindex of 7, co-authored 15 publications receiving 280 citations. Previous affiliations of Prabhav Kalaghatgi include Heidelberg University & Saarland University.
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Journal ArticleDOI
Accurate prediction of neuroblastoma outcome based on miRNA expression profiles
Johannes H. Schulte,Benjamin Schowe,Pieter Mestdagh,Lars Kaderali,Prabhav Kalaghatgi,Stefanie Schlierf,Joëlle Vermeulen,Bent Brockmeyer,Kristian W. Pajtler,Theresa Thor,Katleen De Preter,Franki Speleman,Katharina Morik,Angelika Eggert,Jo Vandesompele,Alexander Schramm +15 more
TL;DR: It is concluded that neuroblastoma patient outcome prediction using miRNA expression is feasible and effective and studies testing miRNA‐based predictors in comparison to and in combination with mRNA and aCGH information should be initiated.
Journal ArticleDOI
Geno2pheno[HCV] - A Web-based Interpretation System to Support Hepatitis C Treatment Decisions in the Era of Direct-Acting Antiviral Agents.
Prabhav Kalaghatgi,Anna Maria Sikorski,Elena Knops,Daniel Rupp,Saleta Sierra,Eva Heger,Maria Neumann-Fraune,Bastian Beggel,Andreas Walker,Jörg Timm,Hauke Walter,Martin Obermeier,Rolf Kaiser,Ralf Bartenschlager,Thomas Lengauer +14 more
TL;DR: The interpretation system geno2pheno (g2p[HCV]), which offers easy-to-use and fast subtype and resistance analysis of HCV sequences, is continuously updated and freely accessible under http://hcv.geno 2pheno.org/index.php.
Journal ArticleDOI
geno2pheno[ngs-freq]: a genotypic interpretation system for identifying viral drug resistance using next-generation sequencing data
Matthias Döring,Joachim Büch,Georg Friedrich,Alejandro Pironti,Prabhav Kalaghatgi,Elena Knops,Eva Heger,Martin Obermeier,Martin Daumer,Alexander Thielen,Rolf Kaiser,Thomas Lengauer,Nico Pfeifer,Nico Pfeifer +13 more
TL;DR: Geno2pheno[ngs-freq] as mentioned in this paper is a web service for rapidly identifying drug resistance in HIV-1 and HCV samples by relying on frequency files that provide the read counts of nucleotides or codons along a viral genome, the timeintensive step of processing raw NGS data is eliminated.
Journal ArticleDOI
Density parameter estimation for finding clusters of homologous proteins—tracing actinobacterial pathogenicity lifestyles
Richard Röttger,Prabhav Kalaghatgi,Peng Sun,Siomar de Castro Soares,Vasco Azevedo,Tobias Wittkop,Jan Baumbach +6 more
TL;DR: The main contribution is a method for identifying a suitable and robust density parameter for protein homology detection without a given gold standard, which is applied to find genes/proteins that are specific for certain actinobacterial lifestyles.
Journal ArticleDOI
Recent increased identification and transmission of HIV-1 unique recombinant forms in Sweden
Ujjwal Neogi,Abu Bakar Siddik,Abu Bakar Siddik,Prabhav Kalaghatgi,Magnus Gisslén,Göran Bratt,Gaetano Marrone,Anders Sönnerborg,Anders Sönnerborg +8 more
TL;DR: Subtyping using four automated tools and phylogenetic analysis by RAxML of pol gene sequences and HIV-1 near full-length genome (HIV-NFLG) sequences and transmission clusters found an increasing trend of URFs in recent years.