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Showing papers by "Pramod Kumar Tiwari published in 2018"


Journal ArticleDOI
TL;DR: In this paper, a quasi-3D approach is used for the modeling of minimum of channel potential that is subsequently used in the drift-diffusion equation to obtain the current expression in sub-threshold regime.
Abstract: In this paper, subthreshold channel potential, current, swing, threshold voltage, and drain-induced barrier lowering models of short-channel tri-gate junctionless field-effect transistors are presented. The models incorporate the effects of both substrate-induced surface potential and variable edges of channel. The quasi-3-D approach is used for the modeling of minimum of channel potential that is subsequently used in the drift–diffusion equation to obtain the current expression in subthreshold regime. Threshold voltage and subthreshold swing models are also based on the minimum of channel potential. The analytical results are compared with the simulation data obtained using 3-D visual TCAD device simulator from Cogenda Pvt., Ltd.

23 citations


Journal ArticleDOI
TL;DR: In this article, a unified drain current model for silicon-nanotube-based ultra-thin double gate-all-around (DGAA) mosfet is presented, which provides a physics-based description of the surface potential, charge density, and drain current.
Abstract: A unified drain current model for silicon-nanotube-based ultra-thin double gate-all-around (DGAA) mosfet is presented in this work. Physics-based, analytical expressions for surface potential and charge density are derived utilizing Fermi-Dirac statistic, one-dimensional density of states (DOS) and Gauss’ law in the ultrathin channel region of the device. Using the derived expressions of surface potential and charge density, a closed-form expression for the drain current under drift-diffusive transport regime is formulated within the purview of gradual channel approximation. The proposed drain current model takes account for two-dimensional carriers’ confinement, which becomes prominent in ultrathin channel devices. The derived model, which is valid for all regions of operation, provides a physics-based description of the surface potential, charge density, and drain current. Output and transfer characteristics of the proposed drain current model have been verified by comparing against results obtained from the three-dimensional numerical simulator for different device parameters. The performance of the proposed drain current model has been further validated with the data presented in reported results. The present drain current model is explicit, analytical, and does not employ any numerical schemes and thus can be readily used in the efficient exploration of any circuit design and simulations.

11 citations


Journal ArticleDOI
TL;DR: The HLA‐A*02 repertoire was investigated in North Indian caste populations using Luminex‐based high‐resolution rSSO method and a striking observation was the high occurrence of A*02:11 at the repertoire level, which may be representation of ancient Austro‐Asiatic genetic pool.

5 citations


Proceedings ArticleDOI
TL;DR: Shushruta Bhunia et al. as discussed by the authors carried out differential proteomic and methylome-based analysis in gallbladder tumors and adjacent non-tumors to identify differentially expressed proteins and global methylation status.
Abstract: Gallbladder cancer (GBC) is a fatal malignancy with widespread geographical variations in incidence worldwide. There are limited studies on systematic molecular profiling of gallbladder cancer in literature. Previously, we carried out differential proteomic and methylome-based analysis in gallbladder tumors and adjacent non-tumors to identify differentially expressed proteins and global methylation status of genes involved in gallbladder cancer. Quantitative tissue proteomics analysis using Isobaric Tags for Relative and Absolute Quantitation (iTRAQ) based Liquid Chromatography-Mass Spectrometry (LC-MS/MS) showed that desmin protein was significantly downregulated (~3 folds) in tumors. Global methylation profiling using Illumina9s Infinium Human Methylation 450 BeadChip array revealed hypermethylation in desmin in gallbladder tumors compared to non-tumor tissue. These findings lead us to further investigate the epigenetic regulation of desmin gene expression in gallbladder cancer. Real-time PCR analysis revealed significant downregulation of desmin (p=0.001) expression in tumors (n=12) as compared to the non-tumor tissue (n=12). Immunohistochemical analysis also showed significantly (p Citation Format: Shushruta Bhunia, Mustafa Ahmed Barbhuiya, Sanjiv Gupta, Braj Raj Shrivastava, Pramod Kumar Tiwari. Downregulation of desmin involves gene promoter hypermethylation in gallbladder cancer [abstract]. In: Proceedings of the AACR International Conference held in cooperation with the Latin American Cooperative Oncology Group (LACOG) on Translational Cancer Medicine; May 4-6, 2017; Sao Paulo, Brazil. Philadelphia (PA): AACR; Clin Cancer Res 2018;24(1_Suppl):Abstract nr A14.