P
Praveen Kumar Vemula
Researcher at National Centre for Biological Sciences
Publications - 109
Citations - 5658
Praveen Kumar Vemula is an academic researcher from National Centre for Biological Sciences. The author has contributed to research in topics: Drug delivery & Medicine. The author has an hindex of 31, co-authored 96 publications receiving 4608 citations. Previous affiliations of Praveen Kumar Vemula include Harvard University & City University of New York.
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Silver-nanoparticle-embedded antimicrobial paints based on vegetable oil
TL;DR: An environmentally friendly chemistry approach to synthesize metal-nanoparticle (MNP)-embedded paint, in a single step, from common household paint, showing excellent antimicrobial properties by killing both Gram-positive human pathogens and Gram-negative bacteria.
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Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway
Rajbir Singh,Sandeep Chandrashekharappa,Sobha R. Bodduluri,Becca V. Baby,Bindu Hegde,Niranjan G. Kotla,Ankita A. Hiwale,Taslimarif Saiyed,Paresh Patel,Matam Vijay-Kumar,Morgan G. I. Langille,Gavin M. Douglas,Xi Cheng,Eric C. Rouchka,Sabine Waigel,Gerald W. Dryden,Houda Alatassi,Huang-Ge Zhang,Bodduluri Haribabu,Praveen Kumar Vemula,Venkatakrishna R. Jala +20 more
TL;DR: It is shown that urolithin A and a synthetic analogue enhance gut barrier function via Nrf2-dependent pathways and mitigate inflammation and colitis in mice, highlighting a potential application for inflammatory bowel diseases.
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Sugar-Derived Phase-Selective Molecular Gelators as Model Solidifiers for Oil Spills†
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Enzyme catalysis: tool to make and break amygdalin hydrogelators from renewable resources: a delivery model for hydrophobic drugs.
TL;DR: A novel approach for the controlled delivery of an antiinflammatory, chemopreventive drug by an enzyme-triggered drug release mechanism via the degradation of encapsulated hydrogels is reported, with a potential impact on pharmaceutical research and molecular design and delivery strategies.
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An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease
Sufeng Zhang,Sufeng Zhang,Joerg Ermann,Joerg Ermann,Marc D. Succi,Marc D. Succi,Marc D. Succi,Allen Zhou,Matthew J. Hamilton,Matthew J. Hamilton,Bonnie Cao,Joshua R. Korzenik,Joshua R. Korzenik,Jonathan N. Glickman,Praveen Kumar Vemula,Laurie H. Glimcher,Giovanni Traverso,Giovanni Traverso,Robert Langer,Jeffrey M. Karp +19 more
TL;DR: Ex vivo analysis of colon tissue samples from patients with ulcerative colitis demonstrated that IT-hydrogel microfibers adhered preferentially to mucosa from inflamed lesions compared with histologically normal sites, suggesting that this new gel-based delivery system could reach and directly treat areas of epithelial inflammation in humans.