P
Premchendar Nandhikonda
Researcher at University of Wisconsin–Milwaukee
Publications - 27
Citations - 907
Premchendar Nandhikonda is an academic researcher from University of Wisconsin–Milwaukee. The author has contributed to research in topics: Calcitriol receptor & Nuclear receptor. The author has an hindex of 16, co-authored 27 publications receiving 679 citations. Previous affiliations of Premchendar Nandhikonda include New Mexico Institute of Mining and Technology & Pacific Northwest National Laboratory.
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Journal ArticleDOI
TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples.
Jiaming Li,Jonathan G. Van Vranken,Laura Pontano Vaites,Devin K. Schweppe,Edward L. Huttlin,Chris Etienne,Premchendar Nandhikonda,Rosa Viner,Aaron M. Robitaille,Andrew Hugin Thompson,Karsten Kuhn,Ian Pike,Ryan Bomgarden,John C. Rogers,Steven P. Gygi,Joao A. Paulo +15 more
TL;DR: A set of isobaric labeling reagents called TMTpro enables deep quantitative comparisons of proteome measurements across 16 samples, and identifies and dose-stratified staurosporine binding to 228 cellular kinases in just one, 18-h experiment.
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Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
Natalie C. Sadler,Premchendar Nandhikonda,Bobbie-Jo M. Webb-Robertson,Charles Ansong,Lindsey N. Anderson,Jordan N. Smith,Richard A. Corley,Aaron T. Wright +7 more
TL;DR: The knowledge of P450 ontogeny is significantly expanded, particularly at the level of individual P450 activity, and these results will be useful for enabling predictive therapeutic dosing, and for avoiding potentially adverse and harmful reactions during maturation from both therapeutic drugs and environmental xenobiotics.
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Elucidation of roles for vitamin B12 in regulation of folate, ubiquinone, and methionine metabolism
Margaret F. Romine,Dmitry A. Rodionov,Dmitry A. Rodionov,Yukari Maezato,Lindsey N. Anderson,Premchendar Nandhikonda,Irina A. Rodionova,Alexandre Carre,Xiaoqing Li,Chengdong Xu,Therese R. W. Clauss,Young-Mo Kim,Thomas O. Metz,Aaron T. Wright +13 more
TL;DR: Using a chemical probe mimic of vitamin B12, a light- and B12-dependent DNA regulator is revealed, and the unexpected discovery of B12 having regulatory involvement in microbial folate, ubiquinone, and methionine processes is made.
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Dual Fluorescent N-Aryl-2,3- naphthalimides: Applications in Ratiometric DNA Detection and White Organic Light-Emitting Devices
TL;DR: From this set of nine DF dyes, 4-fluoronaphthalic amide was selected as a probe for ratiometric detection of DNA and demonstration of panchromatic emission.
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An abiotic fluorescent probe for cardiac troponin I.
TL;DR: Simple cuvette titration experiments in aqueous buffered solution indicate remarkable selectivity for cardiac Troponin in the clinically relevant nM region versus skeletal troponin.