Pyung Lim Han

TL;DR: Data confirm the identity of the rutabaga locus as the structural gene for the Ca2+/CaM-responsive adenylyl cyclase and show that the inactivation of this cyclase leads to a learning and memory defect.

TL;DR: The reisolation of a known learning and memory gene, but with a heretofore unknown expression pattern, strongly supports the postulate that mushroom bodies are principal sites mediating olfactory learning andMemory.

TL;DR: The rutabaga gene encodes one type of adenylyl cyclase (AC) similar in properties to the Type I AC characterized from vertebrate brain, and is postulated to be a molecular coincidence detector capable of integrating information from two independent sources such as the conditioned stimulus (CS) and the unconditioned stimulus (US) delivered to animals during Pavlovian conditioning.

TL;DR: The data suggest that an actin-based process is involved in Notch signaling, and genetic interaction studies show that sanpodo is epistatic to numb.

TL;DR: A novel gene, neuromusculin (nrm), is described that is expressed in sensory mother cells and developing muscles that encodes a member of the immunoglobulin superfamily and is proposed to play a role as a cell adhesion molecule in clustering cells of the peripheral nervous system, neuronal fasciculation, and/or pathfinding.