Qin Zhou

TL;DR: At Memorial Sloan-Kettering Cancer Center, intrahepatic cholangiocarcinoma incidence has increased dramatically in the last 16 years and the recent increase in survival seems largely because of improved nonoperative therapy for unresectable disease.

TL;DR: It is shown that BAP1 knockdown in MPM cell lines affects E2F and Polycomb target genes, which implicate transcriptional deregulation in the pathogenesis of MPM.

TL;DR: It is concluded that translocation of TMPRSS2-ERG is not associated with outcome, and the aggressive clinical features associated with CNI of chromosome 21 reflect generalized aneuploidy and are not due to CNI specifically of rearranged TMPR SS1-ERG.

TL;DR: Because EGFR and KRAS mutations also predict whether tumors are sensitive or resistant, respectively, to EGFR tyrosine kinase inhibitors, they can readily be used in clinical trials to help guide the administration of specific types of adjuvant therapy.

TL;DR: The ability of preoperative computed tomography scan of the abdomen/pelvis and serum CA-125 to predict suboptimal (>1cm residual disease) primary cytoreduction in advanced ovarian, fallopian tube, and peritoneal cancer was assessed.