Q
Qiongling Wang
Researcher at Baylor College of Medicine
Publications - 34
Citations - 4187
Qiongling Wang is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Ryanodine receptor 2 & Ryanodine receptor. The author has an hindex of 22, co-authored 34 publications receiving 3603 citations.
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Journal ArticleDOI
Correction: Corrigendum: The mitochondrial uniporter controls fight or flight heart rate increases
Yuejin Wu,Tyler P. Rasmussen,Olha M. Koval,Mei-ling A. Joiner,Duane D. Hall,Biyi Chen,Elizabeth D. Luczak,Qiongling Wang,Adam G. Rokita,Xander H.T. Wehrens,Long-Sheng Song,Mark E. Anderson +11 more
TL;DR: In Fig. 4c of this Article, the y axis values were wrongly given as 0, 20, 40, 60 and 80 in the middle and the lower panels.
Journal ArticleDOI
Enhanced Sarcoplasmic Reticulum Ca2+ Leak and Increased Na+-Ca2+ Exchanger Function Underlie Delayed Afterdepolarizations in Patients With Chronic Atrial Fibrillation
Niels Voigt,Na Li,Qiongling Wang,Wei Wang,Andrew W. Trafford,Issam Abu-Taha,Qiang Sun,Thomas Wieland,Ursula Ravens,Stanley Nattel,Xander H.T. Wehrens,Dobromir Dobrev +11 more
TL;DR: Enhanced SR Ca2+ leak through CaMKII-hyperphosphorylated RyR2, in combination with larger INCX for a given SR Ca 2+ release and increased diastolic [Ca2+]i-voltage coupling gain, causes AF-promoting atrial delayed afterdepolarizations/triggered activity in cAF patients.
Journal ArticleDOI
Corrigendum: The mitochondrial uniporter controls fight or flight heart rate increases
Yuejin Wu,Tyler P. Rasmussen,Olha M. Koval,Mei Ling A. Joiner,Duane D. Hall,Biyi Chen,Elizabeth D. Luczak,Qiongling Wang,Adam G. Rokita,Xander H.T. Wehrens,Long-Sheng Song,Mark E. Anderson +11 more
TL;DR: In this paper, the y axis values were wrongly given as 0, 20, 40, 60 and 80 in the middle and the lower panels, respectively, in Fig. 4c of this article.
Journal ArticleDOI
Cellular and Molecular Mechanisms of Atrial Arrhythmogenesis in Patients With Paroxysmal Atrial Fibrillation
Niels Voigt,Jordi Heijman,Qiongling Wang,David Y. Chiang,Na Li,Matthias Karck,Xander H.T. Wehrens,Stanley Nattel,Dobromir Dobrev +8 more
TL;DR: Biochemical, functional, and modeling studies point to a combination of increased sarcoplasmic reticulum Ca2+ load related to phospholamban hyperphosphorylation and ryanodine receptor dysregulation and enhanced SERCA2a activity as underlying mechanisms for cellular arrhythmogenesis in pAF patients.
Journal ArticleDOI
Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure
Ralph J. van Oort,Mark McCauley,Sayali S. Dixit,Laetitia Pereira,Yi Yang,Jonathan L. Respress,Qiongling Wang,Angela C. De Almeida,Darlene G. Skapura,Mark E. Anderson,Donald M. Bers,Xander H.T. Wehrens +11 more
TL;DR: This article showed that increased RyR2 phosphorylation by Ca2+/calmodulin-dependent protein kinase II is both necessary and sufficient to promote lethal ventricular arrhythmias.