R
R. M. Kessler
Researcher at National Institutes of Health
Publications - 21
Citations - 2899
R. M. Kessler is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Positron emission tomography & Fluorodeoxyglucose. The author has an hindex of 15, co-authored 21 publications receiving 2850 citations. Previous affiliations of R. M. Kessler include University of California, Irvine.
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Journal ArticleDOI
Positron emission tomography in schizophrenic patients with and without neuroleptic medication
Lynn E. DeLisi,Henry H. Holcomb,Robert M. Cohen,David Pickar,William T. Carpenter,John M. Morihisa,A. Catherine King,R. M. Kessler,Monte S. Buchsbaum +8 more
TL;DR: Positron emission tomography using [18F]2-fluoro-2-deoxy-d-glucose was performed in chronic schizophrenic patients both when medication-free and when medicated with neuroleptics, and there was no change in anterior/posterior metabolic gradients.
Journal ArticleDOI
Tissue signatures with dual-energy computed tomography.
Giovanni Di Chiro,Rodney A. Brooks,R. M. Kessler,Gerald S. Johnston,A.E. Jones,Herdt,William Sheridan +6 more
TL;DR: By providing information on two parameters, dual-energy computed tomography can offer clinically useful tissue signatures for metallic deposits or injected iodine for different normal and abnormal types of brain parenchymal tissues and CSF.
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Clinical history, brain metabolism, and neuropsychological function in Alzheimer's disease
Neal R. Cutler,James V. Haxby,Ranjan Duara,Cheryl L. Grady,Arthur D. Kay,R. M. Kessler,Magesh Sundaram,Stanley I. Rapoport +7 more
TL;DR: The findings suggest that memory and intellectual deficits are reflected in reductions of brain metabolism in some brain regions in mild to moderate forms of Alzheimer's disease and that, in the late, severe form of the disease, reductions occur consistently throughout the brain.
Journal ArticleDOI
Increased temporal lobe glucose use in chronic schizophrenic patients.
Lynn E. DeLisi,Monte S. Buchsbaum,Henry H. Holcomb,Katharine C. Langston,A. Catherine King,R. M. Kessler,David Pickar,William T. Carpenter,John M. Morihisa,Richard Margolin,Daniel R. Weinberger +10 more
TL;DR: Patients with schizophrenia had significantly greater metabolic activity in the left than the right anterior temporal lobe, and the extent of this lateralization was in proportion to the severity of psychopathology.
Journal ArticleDOI
Alternative statistical models for the examination of clinical positron emission tomography/fluorodeoxyglucose data.
C. M. Clark,Richard E. Carson,R. M. Kessler,Richard Margolin,Monte S. Buchsbaum,Lynn E. DeLisi,Catherine King,Robert M. Cohen +7 more
TL;DR: A method for partitioning metabolic variability found in positron emission tomography/[18F]fluorodeoxyglucose studies and the method of Q-component analysis for the identification of strong- and weak-pattern subjects is described.