R
R. Paul Maguire
Researcher at Pfizer
Publications - 11
Citations - 10826
R. Paul Maguire is an academic researcher from Pfizer. The author has contributed to research in topics: Cerebral blood flow & Medicine. The author has an hindex of 9, co-authored 9 publications receiving 8468 citations. Previous affiliations of R. Paul Maguire include University Medical Center Groningen.
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Journal ArticleDOI
An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest.
Rahul S. Desikan,Florent Ségonne,Bruce Fischl,Bruce Fischl,Brian T. Quinn,Bradford C. Dickerson,Deborah Blacker,Randy L. Buckner,Randy L. Buckner,Anders M. Dale,R. Paul Maguire,Bradley T. Hyman,Marilyn S. Albert,Ronald J. Killiany +13 more
TL;DR: An automated labeling system for subdividing the human cerebral cortex into standard gyral-based neuroanatomical regions is both anatomically valid and reliable and may be useful for both morphometric and functional studies of the cerebral cortex.
Journal ArticleDOI
MRI-derived measurements of human subcortical, ventricular and intracranial brain volumes: Reliability effects of scan sessions, acquisition sequences, data analyses, scanner upgrade, scanner vendors and field strengths
Jorge Jovicich,Silvester Czanner,Xiao Han,David H. Salat,Andre van der Kouwe,Brian T. Quinn,Jenni Pacheco,Marilyn S. Albert,Ronald J. Killiany,Deborah Blacker,R. Paul Maguire,H. Diana Rosas,Nikos Makris,Randy L. Gollub,Anders M. Dale,Bradford C. Dickerson,Bruce Fischl,Bruce Fischl +17 more
TL;DR: Results suggest that volumes derived from automated segmentation of T1-weighted structural images are reliable measures within the same scanner platform, even after upgrades; however, combining data across platform and across field-strength introduces a bias that should be considered in the design of multi-site studies, such as clinical drug trials.
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Kinetic Modeling of the Serotonin 5-HT1B Receptor Radioligand [11C]P943 in Humans
Jean-Dominique Gallezot,Nabeel Nabulsi,Alexander Neumeister,Beata Planeta-Wilson,Wendol Williams,Tarun Singhal,Sunhee Kim,R. Paul Maguire,Timothy J. McCarthy,J. James Frost,Yiyun Huang,Yu-Shin Ding,Richard E. Carson +12 more
TL;DR: The results show that [11C]P943 provides quantitative measurements of 5-HT1B binding potential, and the MRTM2 model provided the best correlation with MA1 binding-potential estimates.
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Dissociable effects of methylphenidate, atomoxetine and placebo on regional cerebral blood flow in healthy volunteers at rest: A multi-class pattern recognition approach
Andre F. Marquand,Owen O'Daly,Sara De Simoni,David C. Alsop,R. Paul Maguire,Steven Williams,Fernando Zelaya,Mitul A. Mehta +7 more
TL;DR: The results demonstrate that combining ASL and PR yields a sensitive method for detecting the effects of these drugs and provides insights into the regional distribution of brain networks potentially modulated by these compounds.
Journal ArticleDOI
Arterial Transit Time Effects in Pulsed Arterial Spin Labeling CBF Mapping: Insight From a PET and MR Study in Normal Human Subjects
Maolin Qiu,R. Paul Maguire,Jagriti Arora,Beata Planeta-Wilson,David Weinzimmer,Jinghua Wang,Yuenan Wang,Hyeonjin Kim,Nallakkandi Rajeevan,Yiyun Huang,Richard E. Carson,R. Todd Constable +11 more
TL;DR: ASL ATTs were estimated on a per‐voxel basis using data measured by both ASL and positron emission tomography in the same subjects to provide a quantitative relationship between ATT and the ASL imaging geometry and yield an assessment of the assumptions commonly used in ASL Imaging.