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Bradford C. Dickerson
Researcher at Harvard University
Publications - 344
Citations - 36665
Bradford C. Dickerson is an academic researcher from Harvard University. The author has contributed to research in topics: Dementia & Primary progressive aphasia. The author has an hindex of 76, co-authored 293 publications receiving 29599 citations. Previous affiliations of Bradford C. Dickerson include Brigham and Women's Hospital & Rush University.
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Journal ArticleDOI
An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest.
Rahul S. Desikan,Florent Ségonne,Bruce Fischl,Bruce Fischl,Brian T. Quinn,Bradford C. Dickerson,Deborah Blacker,Randy L. Buckner,Randy L. Buckner,Anders M. Dale,R. Paul Maguire,Bradley T. Hyman,Marilyn S. Albert,Ronald J. Killiany +13 more
TL;DR: An automated labeling system for subdividing the human cerebral cortex into standard gyral-based neuroanatomical regions is both anatomically valid and reliable and may be useful for both morphometric and functional studies of the cerebral cortex.
Journal ArticleDOI
Reliability of MRI-derived measurements of human cerebral cortical thickness: the effects of field strength, scanner upgrade and manufacturer.
Xiao Han,Jorge Jovicich,David H. Salat,Andre van der Kouwe,Brian T. Quinn,Silvester Czanner,Evelina Busa,Jenni Pacheco,Marilyn S. Albert,Marilyn S. Albert,Ronald J. Killiany,Paul Maguire,Diana Rosas,Nikos Makris,Anders M. Dale,Bradford C. Dickerson,Bruce Fischl,Bruce Fischl +17 more
TL;DR: It is demonstrated that MRI-derived cortical thickness measures are highly reliable when MRI instrument and data processing factors are controlled but that it is important to consider these factors in the design of multi-site or longitudinal studies, such as clinical drug trials.
Journal ArticleDOI
The Cortical Signature of Alzheimer's Disease: Regionally Specific Cortical Thinning Relates to Symptom Severity in Very Mild to Mild AD Dementia and is Detectable in Asymptomatic Amyloid-Positive Individuals
Bradford C. Dickerson,Akram Bakkour,David H. Salat,Eric Feczko,Jenni Pacheco,Douglas N. Greve,Fran Grodstein,Christopher I. Wright,Christopher I. Wright,Deborah Blacker,H. Diana Rosas,Reisa A. Sperling,Alireza Atri,John H. Growdon,Bradley T. Hyman,John C. Morris,Bruce Fischl,Bruce Fischl,Randy L. Buckner,Randy L. Buckner +19 more
TL;DR: In this paper, an exploratory map of cortical thinning in mild Alzheimer's disease was used to define regions of interest that were applied in a hypothesis-driven fashion to other subject samples.
Journal ArticleDOI
Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD
Bradford C. Dickerson,David H. Salat,Douglas N. Greve,Elizabeth F. Chua,Erin Rand-Giovannetti,Dorene M. Rentz,Lars Bertram,Kristina Mullin,Rudolph E. Tanzi,Deborah Blacker,Marilyn S. Albert,Reisa A. Sperling +11 more
TL;DR: It is hypothesized that there is a phase of increased medial temporal lobe activation early in the course of prodromal Alzheimer disease followed by a subsequent decrease as the disease progresses.
Journal ArticleDOI
Tau positron emission tomographic imaging in aging and early Alzheimer disease
Keith A. Johnson,Aaron P. Schultz,Rebecca A. Betensky,J. Alex Becker,Jorge Sepulcre,Dorene M. Rentz,Dorene M. Rentz,Elizabeth C. Mormino,Jasmeer P. Chhatwal,Jasmeer P. Chhatwal,Rebecca E. Amariglio,Rebecca E. Amariglio,Kate V. Papp,Kate V. Papp,Gad A. Marshall,Gad A. Marshall,Mark W. Albers,Samantha Mauro,Lesley C. Pepin,Jonathan Alverio,Kelly Judge,Marlie Philiossaint,Timothy M. Shoup,Daniel Yokell,Bradford C. Dickerson,Teresa Gomez-Isla,Bradley T. Hyman,Neil Vasdev,Reisa A. Sperling +28 more
TL;DR: Detection of focal brain tau deposition during life could greatly facilitate accurate diagnosis of Alzheimer disease (AD), staging and monitoring of disease progression, and development of disease‐modifying therapies.