Rainer G. Ulrich

TL;DR: The pathways and data requirements for a qualitative risk assessment for the emergence of CCHFV in livestock in Europe are discussed and a risk map approach is proposed based on layers that include the potential routes of release together with the main components for exposure, namely the distributions of the tick vectors, the small vertebrate host reservoirs and the livestock.

TL;DR: A suppressable stop codon located between the HBV core and the C-terminally fused hantavirus sequence restored the ability to form particles (‘mosaic particles’) and allowed the formation of particles built up by the core protein itself and theHBV core-Puumala nucleocapsid- readthrough protein.

TL;DR: Mapping by overlapping peptides (PEPSCAN) confirmed a complex recognition pattern for most analyzed mAbs and revealed the existence of several, partially overlapping, and discontinuous B-cell epitopes of Puumala hantavirus N.

TL;DR: The present study clearly demonstrates that a high percentage of domestic pigs in Germany have had contact with HEV, and the presence of anti-HEV-free herds may indicate that it is feasible to establish and sustain HEV- free pig herds.

TL;DR: The virus inactivation and depletion methods described herein are suitable to prepare non-infectious samples for further use in immunological, virological and cell-biological assays.