R
Rajani Mathur
Researcher at Delhi Institute of Pharmaceutical Sciences and Research
Publications - 48
Citations - 879
Rajani Mathur is an academic researcher from Delhi Institute of Pharmaceutical Sciences and Research. The author has contributed to research in topics: Insulin resistance & Diabetes mellitus. The author has an hindex of 15, co-authored 42 publications receiving 746 citations. Previous affiliations of Rajani Mathur include University of Delhi & All India Institute of Medical Sciences.
Papers
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Journal ArticleDOI
Evaluation of the effect of Withania somnifera root extracts on cell cycle and angiogenesis
Rajani Mathur,Suresh Kumar Gupta,Neeta Singh,Sandeep Mathur,Vinod Kochupillai,Thirumurthy Velpandian +5 more
TL;DR: Findings suggest that the roots of Withania somnifera possess cell cycle disruption and anti-angiogenic activity, which may be a critical mediator for its anti-cancer action.
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Cytotoxic and antitumor effects of brucine on Ehrlich ascites tumor and human cancer cell line.
TL;DR: It is suggested that brucine can be used as a potential anticancer agent as an antimetastatic and anti-angiogenic agent in vitro and in vivo.
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Development and validation of a simple liquid chromatographic method with ultraviolet detection for the determination of imatinib in biological samples.
Thirumurthy Velpandian,Rajani Mathur,Nitin Agarwal,Brijesh Arora,Lalit Kumar,Suresh Kumar Gupta +5 more
TL;DR: A rapid and sensitive HPLC method with UV detection for the estimation of imatinib from the plasma of patients with chronic myeloid leukemia (CML) and the robustness of the method was checked by conducting first dose pharmacokinetics on blood samples from four patients who had been administered Gleevec in an oral dose.
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Genistein ameliorates cardiac inflammation and oxidative stress in streptozotocin-induced diabetic cardiomyopathy in rats
Suresh Kumar Gupta,Shirish Dongare,Rajani Mathur,Ipseeta Ray Mohanty,Sushma Srivastava,Sandeep Mathur,Tapas Chandra Nag +6 more
TL;DR: Genistein treatment ameliorated the ultrastructural degenerative changes in the cardiac tissues as compared to the diabetic control, demonstrating that genistein restored the integrity of the diabetic myocardium by virtue of its anti-inflammatory and antioxidant effects.
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Antitumor properties of Boswellic acid against Ehrlich ascites cells bearing mouse
TL;DR: Light is shed on the potent antitumor property of the boswellic acid and can be extended further to develop therapeutic protocols for treatment of cancer.