R
Raquel S. Carreira
Researcher at San Diego State University
Publications - 7
Citations - 794
Raquel S. Carreira is an academic researcher from San Diego State University. The author has contributed to research in topics: Mitochondrion & Autophagy. The author has an hindex of 7, co-authored 7 publications receiving 725 citations.
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Journal ArticleDOI
LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection.
Hua Yuan,Cynthia N. Perry,Chengqun Huang,Eri Iwai-Kanai,Raquel S. Carreira,Christopher C. Glembotski,Roberta A. Gottlieb +6 more
TL;DR: The notion that autophagy is a cytoprotective response to LPS-induced cardiomyocyte injury is supported; additional studies are needed to determine the therapeutic implications.
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Autophagy in health and disease. 5. Mitophagy as a way of life
TL;DR: The failure to maintain mitochondrial quality control through mitophagy may explain why the heart, brain, and components of the immune system are most vulnerable to dysfunction as organisms age.
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MitoTimer: A novel tool for monitoring mitochondrial turnover
Genaro Hernandez,Christine A Thornton,Aleksandr Stotland,Diana Lui,Jon Sin,Jennifer Ramil,Najib Magee,Allen M. Andres,Giovanni Quarato,Raquel S. Carreira,M. Richard Sayen,Roland Wolkowicz,Roberta A. Gottlieb +12 more
TL;DR: In this article, the authors used a tetracycline-inducible promoter construct to regulate the expression of fluorescent Timer, a fluorescent reporter for mitochondrial dynamics, which can reveal new insights into mitochondrial dynamics within cells.
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Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells
TL;DR: A physiologic function for CypD and the MPT in the regulation of starvation-induced autophagy is suggested and may represent a homeostatic mechanism for cellular and mitochondrial quality control.
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Mitochondrial therapeutics for cardioprotection.
TL;DR: Interventions that modulate mitochondrial turnover, including pharmacologic agents, exercise, and caloric restriction are discussed as a means to improve mitochondrial quality control, ameliorate cardiovascular dysfunction, and enhance longevity.