R
Raymond J. MacDonald
Researcher at University of Texas Southwestern Medical Center
Publications - 124
Citations - 31069
Raymond J. MacDonald is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Gene expression & Pancreas. The author has an hindex of 56, co-authored 121 publications receiving 30650 citations. Previous affiliations of Raymond J. MacDonald include University of Pennsylvania & Howard Hughes Medical Institute.
Papers
More filters
Journal ArticleDOI
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.
TL;DR: In this article, the rat pancreas RNA was used as a source for the purification of alpha-amylase messenger ribonucleic acid (RBA) using 2-mercaptoethanol.
Journal ArticleDOI
Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes
Don W. Cleveland,Margaret A. Lopata,Raymond J. MacDonald,Nicholas J. Cowan,William J. Rutter,Marc W. Kirschner +5 more
TL;DR: Bacterial clones containing inserted DNA sequences specific for α- Tubulin, β-tubulin,β-Actin and γ-actin have been constructed from mRNA of embryonic chick brain and are able to hybridize under stringent conditions to DNA of all vertebrates tested, as well as to sea urchin DNA, but not to yeast DNA.
Journal ArticleDOI
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
Yoshiya Kawaguchi,Bonnie Cooper,Maureen Gannon,Michael Ray,Raymond J. MacDonald,Christopher V.E. Wright +5 more
TL;DR: Rec recombination-based lineage tracing in vivo is used to show that PTF1a is expressed at these early stages in the progenitors of pancreatic ducts, exocrine and endocrine cells, rather than being an exocrine-specific gene as previously described.
Book ChapterDOI
Isolation of RNA using guanidinium salts.
Journal ArticleDOI
Tissue-specific expression of the rat pancreatic elastase I gene in transgenic mice.
TL;DR: Transfer of a 23 kb genomic DNA segment containing the rat elastase I gene to a foreign chromosomal location in the mouse can give rise to qualitatively and quantitatively normal expression.